Southern Illinois vs. Indiana State: College Football Week 10 Prediction, Picks & Odds
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Southern Illinois vs. Indiana State: Detailed Breakdown
Matchup overview: College Football Week 10
- Teams: Southern Illinois vs. Indiana State
- Date: Saturday, November 7, 2026
- Time: 6:00PM ET
- Venue: Memorial Stadium (Terre Haute, IN)
Current betting odds
- Spread: Southern Illinois (-4.5, +100), Indiana State (+4.5, -138)
- Moneyline: Southern Illinois -163, Indiana State +141
- Total (Over/Under): 57.5 points (-111/-125)
Dimers’ win probabilities
- Southern Illinois: 63.8%
- Indiana State: 36.2%
These probabilities come from two machine learning models that assess more than 100 data points for each college football matchup, combining their outputs to project all our major betting markets.
Projected final score
Our predicted final score for this college football matchup is Southern Illinois 30-26 Indiana State.
This prediction draws on each team's scoring trends and player stats, weighed across both of our data models
Our Prediction: Who Wins?
The numbers give the Southern Illinois a win probability of 63.8%, while the Indiana State have a win probability of 36.2%.
Summary
Southern Illinois faces off against Indiana State in college football action at Memorial Stadium (Terre Haute, IN) on Saturday, November 7, 2026.
Our Southern Illinois vs. Indiana State predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.
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For further insights, explore our expert college football predictions and the best college football bets today, while our in-depth analysis includes college football props, college football futures, college football odds, and the latest college football news.

