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Read Article College football picks today: Week 1 Sunday best bets include Louisville vs. Mississippi play [9/6/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Editor
Get college football picks and best bets for Sunday, September 6, 2026.
Today’s college football picks for September 6, 2026 are here, with Louisville vs. Mississippi among the top plays identified by our model across Sunday’s college football action.
Dimers’ predictive analytics engine runs 24/7, searching the latest football odds to uncover real betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of college football picks today [9/6, updated 2:22PM ET]
Below, you’ll find today’s college football best bets, ranked by edge for Sunday, September 6, 2026.
Louisville vs. Mississippi Under 55.5 points (-110)
- Edge: 5.1%
- Probability: 57.5%
- Matchup: Louisville vs. Mississippi (7:30PM ET)
Our model has identified value on Under 55.5 points in Louisville vs. Mississippi at -110 odds. A 57.5% probability produces an edge of 5.1%, making this the strongest play for today's college football slate.
Louisville ML (+210)
- Edge: 4.6%
- Probability: 36.8%
- Matchup: Louisville vs. Mississippi (7:30PM ET)
Louisville ML carries a 4.6% edge and a probability of 36.8% at +210 odds, according to our model.
Washington State vs. Washington Under 51.5 points (-105)
- Edge: 4.4%
- Probability: 55.6%
- Matchup: Washington State vs. Washington (4:00PM ET)
Washington State vs. Washington Under 51.5 points at -105 odds shows a 4.4% edge, supported by a 55.6% probability in simulations.
NCAAF best bets summary: Sunday, 9/6/2026
As of 2:22PM ET, here are our top college football bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Prob. |
|---|---|---|---|---|
| Louisville vs. Mississippi | Under 55.5 points | -110 @ BetMGM | 5.1% | 57.5% |
| Louisville vs. Mississippi | Louisville ML | +210 @ DraftKings | 4.6% | 36.8% |
| Washington State vs. Washington | Under 51.5 Points | -105 @ FanDuel | 4.4% | 55.6% |
List of upcoming college football games to bet on now
- South Carolina State vs. Florida A&M (3:00PM ET, Sunday)
- Washington State vs. Washington (4:00PM ET, Sunday)
- Wisconsin vs. Notre Dame (7:30PM ET, Sunday)
- Louisville vs. Mississippi (7:30PM ET, Sunday)
See How Dimers Pro Enhances Your Best Bets
Discover the difference our best bets make with Dimers Pro. Check out this explainer video to see how you can gain an edge.
College football offer for Week 1
Make the most of the picks in this article—including Under 55.5 points—with the Underdog Fantasy offer below:
Conclusion
Our college football best bets are locked and loaded for September 6, 2026, featuring plays such as under 55.5 points in the Louisville vs. Mississippi matchup and Louisville ML. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
Ryan Leaver specializes in sports betting analysis across the NBA, NFL, college football, college basketball, and soccer. Drawing on advanced statistical models, simulations, and historical data, he produces game previews, betting picks, player prop analysis, and futures coverage to help bettors make more informed decisions.
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