Louisville vs. Memphis prediction, odds, pick for Nov. 15, 2026

Louisville is favored to beat Memphis at FedExForum on Sunday (1:00 PM ET), according to Dimers' men's college basketball model.

Our Louisville vs. Memphis prediction gives the Cardinals a 74.6% chance of winning, but the latest odds suggest there's betting value on Memphis to cover at +8.5.

Louisville vs. Memphis key predictions

• Predicted score: Louisville 83-76 Memphis
• Louisville win probability: 74.6%
• Memphis win probability: 25.4%
• Memphis +8.5 spread: 54.8% cover probability
• Under 162.5 points: 53.8% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

Louisville vs. Memphis odds

These are the best available odds across the moneyline, spread, and total points markets.

• Louisville moneyline: -400 (FanDuel)
• Memphis moneyline: +320 (BetMGM)
• Louisville -8.5: -110 (Caesars Sportsbook)
• Memphis +8.5: -105 (BetMGM)
• Over 162.5 points: -115 (FanDuel)
• Under 162.5 points: -105 (FanDuel)

Odds are subject to change and may vary by location.

Louisville vs. Memphis pick: Memphis +8.5 (-105)

Our model makes Louisville the more likely winner, but our best value bet is the Tigers to cover the +8.5 spread at -105 on BetMGM.

Those odds give Memphis an implied cover probability of 51.2%, while our model rates it at 54.8%.

That's a 3.6% edge, the biggest across the moneyline, spread, and total points markets.

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Louisville vs. Memphis game details

• Matchup: Louisville Cardinals vs. Memphis Tigers
• Date: Sunday, November 15, 2026
• Time: 1:00 PM ET
• Venue: FedExForum

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.