Coastal Carolina vs. Duke prediction, odds, pick for Nov. 5, 2026

Duke is favored to beat Coastal Carolina at Cameron Indoor Stadium on Thursday (8:00 PM ET), according to Dimers' men's college basketball model.

Our Coastal Carolina vs. Duke prediction gives Duke a 99.4% chance of winning, but the latest odds suggest there's betting value on Coastal Carolina to cover at +41.5.

Coastal Carolina vs. Duke key predictions

• Predicted score: Duke 92-59 Coastal Carolina
• Duke win probability: 99.4%
• Coastal Carolina win probability: 0.6%
• Coastal Carolina +41.5 spread: 59.0% cover probability
• Over 150.5 points: 51.8% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

Coastal Carolina vs. Duke odds

Here are the best available odds across the moneyline, spread, and total points markets we track.

• Coastal Carolina moneyline: +8000 (FanDuel)
• Duke moneyline: -10000 (BetMGM)
• Coastal Carolina +41.5: -110 (FanDuel)
• Duke -41.5: -105 (BetMGM)
• Over 150.5 points: -105 (DraftKings)
• Under 150.5 points: -105 (FanDuel)

Odds are subject to change and may vary by location.

Coastal Carolina vs. Duke pick: Coastal Carolina +41.5 (-110)

Our model makes Duke the likelier winner, but our best value bet is Coastal Carolina to cover the +41.5 spread at -110 on FanDuel.

Those odds give Coastal Carolina an implied cover probability of 52.4%, while our model puts it at 59.0%.

That's a 6.6% edge, the largest across the moneyline, spread, and total points markets for this game.

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Coastal Carolina vs. Duke game details

• Matchup: Coastal Carolina Chanticleers vs. Duke Blue Devils
• Date: Thursday, November 5, 2026
• Time: 8:00 PM ET
• Venue: Cameron Indoor Stadium

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.