Cubs vs. Guardians Prediction, Picks and Odds

Our detailed prediction and analysis for the Cubs vs. Guardians MLB game on April 5, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
Start your FREE 3-Day trial of Dimers Pro
FINAL
MLB
Add this game to My Favorites
FINAL
Add this game to My Favorites
MLB sport icon
MLB
Cubs
5
6
Apr 5, 5:40PM Progressive Field
Guardians
Apr 5, 5:40PM Progressive Field
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
1 2 3 4 5 6 7 8 9 RHE
Cubs
0 0 1 0 0 2 0 1 1 5 7 0
Guardians
0 0 0 0 0 3 0 3 X 6 9 0
Live Probabilities
Moneyline
Over / Under
Run Line
Cubs CHC
Win %
0%
100%
Guardians CLE
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Carson Kelly strikes out swinging.
Quick Box Score
Hitting
Pitching
Cubs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 N. Hoerner 2B3110020.3331.267
2 A. Bregman 3B4000011.0000.200
3 S. Kingery PR0000000.0000.000
4 C. Kelly C4110012.2500.650
5 M. Busch 1B3000011.0000.250
6 D. Swanson SS4112102.2501.250
7 M. Shaw RF3111111.3331.833
8 P. Crow-Armstrong CF4010000.2500.500
9 M. Ballesteros PH1000001.0000.000
Guardians Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 S. Kwan CF5110001.2000.600
2 A. Martínez LF3100010.0000.250
3 J. Ramírez 3B4000000.0000.000
4 C. Kayfus RF22221001.0003.500
5 C. DeLauter DH3111001.3330.583
6 R. Hoskins 1B2100021.0000.500
7 G. Arias SS4022000.5001.000
8 A. Hedges C4021000.5001.250
9 B. Rocchio 2B4000001.0000.000

Featured offers

Swipe iconSwipe across to view more offers
logo
FEATURED
New DraftKings Customers: Bet $5, Get $200 in Bonus Bets Instantly
T&Cs apply.
How to claim
logo
RECOMMENDED
Double Your Winnings on your Next 10 Wagers. Up to $25 Max Bet Per Boost
T&Cs apply.
How to claim
logo
NEW PLAYERS
Bet $5, Get $150 in Bonus Bets if your bet wins!
T&Cs apply.
How to claim
logo
RECOMMENDED
Deposit $20, Get $50 in Trading Bonus!
T&Cs apply.
How to claim
logo
LIMITED-TIME
Register with code DIMERS150 to unlock $150 in bonus bets by winning your first $10 bet
T&Cs apply.
How to claim
logo
NEW PLAYERS
Get $350 in Bonus Bets Guaranteed - When You Bet $5 for 7 Days!
T&Cs apply.
How to claim
logo
RECOMMENDED
Use Code DIMERS to Get up to $100 in Bonuses by Trading in Your First 7 Days!
T&Cs apply.
How to claim
logo
TRENDING
Bet $10 Get $365 Win or Lose
T&Cs apply.
How to claim
logo
NEW PLAYERS
Get Up To $250 Back in Bonus Bets If Your First Bet Loses
T&Cs apply.
How to claim

Cubs vs. Guardians: Detailed Breakdown

Matchup Overview

  • Teams: Cubs vs. Guardians
  • Date: Sunday, April 5, 2026
  • Time: 1:40 PM ET
  • Venue: Progressive Field

Current Betting Odds

  • Spread: Cubs favored at -1.5
  • Total (Over/Under): 7
  • Moneyline Odds: Cubs -118, Guardians +120

Dimers' Win Probabilities

  • Cubs: 52%
  • Guardians: 48%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 52%, while the Guardians have a win probability of 48%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cubs are more likely to beat the Guardians in the MLB game at Progressive Field on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Guardians predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.