Cubs vs. Cardinals Prediction, Picks and Odds

Our detailed prediction and analysis for the Cubs vs. Cardinals MLB game on July 28, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
MLB
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MLB
Cubs
Colin Rea 7-7, 4.86 ERA
vs.
Jul 28, 7:45 PM ET Busch Stadium
Cardinals
Michael McGreevy 4-8, 3.07 ERA
Jul 28, 7:45 PM ET Busch Stadium
Pre-Game Probabilities Last Update: July 28, 2026, 2:46 PM ET

Moneyline

Moneyline
Win %
  • Cubs
    50.0%
    NovigNovig
  • Cardinals
    50.0%
    NovigNovig
Weather Forecast
Last Updated: July 28, 2026, 7:15 AM ET
Patchy rain nearby weather icon
73°FPatchy rain nearby
RoofNone
Humidity89%
Wind speed1mph
Cloud cover81%
Dew point70°F
Wind directionSSW

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Cubs vs. Cardinals: Detailed Breakdown

Matchup Overview

  • Teams: Cubs vs. Cardinals
  • Date: Tuesday, July 28, 2026
  • Time: 7:45 PM ET
  • Venue: Busch Stadium

Current Betting Odds

  • Spread: Cubs favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: Cubs -108, Cardinals +106

Dimers' Win Probabilities

  • Cubs: 50%
  • Cardinals: 50%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 50%, while the Cardinals have a win probability of 50%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Cardinals are more likely to beat the Cubs in the MLB game at Busch Stadium on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.