Santos Laguna vs. San Luis Prediction, Picks and Odds

Dimers' prediction and analysis for the Santos Laguna vs. San Luis Liga MX match on April 22, 2026 includes win probabilities and picks for the biggest betting markets. Get Dimers Pro for full access.
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LIGA MX
Santos Laguna
0
2
Estadio Alfonso Lastras
San Luis
Estadio Alfonso Lastras
San LuisASL
Score Summary
Santos LagunaSAN
L. Flores (86')
Soccer ball icon
Joao Pedro Galvao (90')
Soccer ball icon
Live Probabilities
Win %
  • San Luis
    100.0%
  • Draw
    0.0%
  • Santos Laguna
    0.0%
Win Probability
Match Timeline
  1. 90'
    Substitution
    Substitution for Atl. San Luis: J. Dominguez replaces O. Macias
  2. 90'
    Substitution
    Substitution for Santos Laguna: J. Abella replaces K. Picon
  3. 90'
    Substitution
    Substitution for Santos Laguna: R. Sordo replaces F. Villalba
  4. 90'
    Substitution
    Substitution for Santos Laguna: T. Jimenez replaces S. Mariscal Murra
  5. 90'
    Soccer ball icon
    Goal scored for Atl. San Luis by Joao Pedro Galvao, assisted by A. Duarte
    0-2
  6. 86'
    Soccer ball icon
    Goal scored for Atl. San Luis by L. Flores, assisted by Joao Pedro Galvao
    0-1
  7. 81'
    Substitution
    Substitution for Santos Laguna: C. Dajome replaces E. Bullaude
  8. 77'
    Substitution
    Substitution for Atl. San Luis: Juanpe replaces E. Aguila
  9. 76'
    Substitution
    Substitution for Atl. San Luis: S. Munoz replaces D. Rodriguez
  10. 70'
    Substitution
    Substitution for Santos Laguna: L. Gomez replaces A. Lopez
  11. 64'
    Yellow Card
    E. Aguila (Atl. San Luis) cautioned
  12. 57'
    Substitution
    Substitution for Atl. San Luis: A. Duarte replaces R. Meraz
  13. 50'
    Yellow Card
    R. Meraz (Atl. San Luis) cautioned
  14. 46'
    Substitution
    Substitution for Atl. San Luis: L. Flores replaces Lucas Esteves
  15. 40'
    Yellow Card
    Joao Pedro Galvao (Atl. San Luis) cautioned
  16. 37'
    Yellow Card
    A. Lopez (Santos Laguna) cautioned
  17. 17'
    Yellow Card
    A. Sanchez (Atl. San Luis) cautioned

Santos Laguna vs. San Luis: Match prediction & analysis

Match overview

  • Teams: Santos Laguna vs. San Luis
  • Date: Wednesday, April 22, 2026
  • Time: 9:00 PM ET
  • Venue: Estadio Alfonso Lastras

Current betting odds

  • Moneyline: Santos Laguna +290, San Luis -110, draw +300
  • Total (Over/Under): 2.5 goals (-188/+140)

Dimers' win & correct score probabilities

  • Santos Laguna: 20.7%
  • San Luis: 57.9%
  • Draw: 21.4%

These probabilities are generated using Dimers' Liga MX data model, which predicts the most likely outcomes for all major betting markets.

Most likely correct score: Santos Laguna 1-2 San Luis (9.9%)

Correct score projections are based on expected scoring patterns. A team can have a higher chance of winning overall, even if the single most likely scoreline is a draw or narrow result.

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  • Moneyline probabilities
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Who will win Santos Laguna vs. San Luis? Prediction & correct score

San Luis is the most likely winner of this match with a win probability of 57.9%.

The most likely correct score is Santos Laguna 1-2 San Luis.

But the most likely outcomes aren't always the best betting opportunities.

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