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Santos Laguna vs. San Luis Prediction, Picks and Odds
Dimers' prediction and analysis for the Santos Laguna vs. San Luis Liga MX match on April 22, 2026 includes win probabilities and picks for the biggest betting markets. Start your free 3-day trial of Dimers Pro for full access.
FINAL
LIGA MX
FINAL
LIGA MX
0
2
Apr 22, 9:00 PM ET Estadio Alfonso Lastras
Apr 22, 9:00 PM ET Estadio Alfonso Lastras
In-Play ProbabilitiesIn-Play
Pre-Game PredictionsPre-Game
Pro Bets
Score Summary
L. Flores (86')
Joao Pedro Galvao (90')
Live Probabilities
Moneyline
Over / Under
- San Luis
- Santos Laguna
Win Probability
Match Timeline
Substitution for Atl. San Luis: J. Dominguez replaces O. Macias
Substitution for Santos Laguna: J. Abella replaces K. Picon
Substitution for Santos Laguna: R. Sordo replaces F. Villalba
Substitution for Santos Laguna: T. Jimenez replaces S. Mariscal Murra
Goal scored for Atl. San Luis by Joao Pedro Galvao, assisted by A. Duarte
0-2
Goal scored for Atl. San Luis by L. Flores, assisted by Joao Pedro Galvao
0-1
Substitution for Santos Laguna: C. Dajome replaces E. Bullaude
Substitution for Atl. San Luis: Juanpe replaces E. Aguila
Substitution for Atl. San Luis: S. Munoz replaces D. Rodriguez
Substitution for Santos Laguna: L. Gomez replaces A. Lopez
E. Aguila (Atl. San Luis) cautioned
Substitution for Atl. San Luis: A. Duarte replaces R. Meraz
R. Meraz (Atl. San Luis) cautioned
Substitution for Atl. San Luis: L. Flores replaces Lucas Esteves
Joao Pedro Galvao (Atl. San Luis) cautioned
A. Lopez (Santos Laguna) cautioned
A. Sanchez (Atl. San Luis) cautioned
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Santos Laguna vs. San Luis: Match prediction & analysis
Match overview
- Teams: Santos Laguna vs. San Luis
- Date: Wednesday, April 22, 2026
- Time: 9:00 PM ET
- Venue: Estadio Alfonso Lastras
Current betting odds
- Moneyline: Santos Laguna +290, San Luis -110, draw +300
- Total (Over/Under): 2.5 goals (-188/+140)
Dimers' win & correct score probabilities
- Santos Laguna: 20.7%
- San Luis: 57.9%
- Draw: 21.4%
These probabilities are generated using Dimers' Liga MX data model, which predicts the most likely outcomes for all major betting markets.
Most likely correct score: Santos Laguna 1-2 San Luis (9.9%)
Correct score projections are based on expected scoring patterns. A team can have a higher chance of winning overall, even if the single most likely scoreline is a draw or narrow result.
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- Moneyline probabilities
- Total goals probabilities
- Correct score probabilities
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Who will win Santos Laguna vs. San Luis? Prediction & correct score
San Luis is the most likely winner of this match with a win probability of 57.9%.
The most likely correct score is Santos Laguna 1-2 San Luis.
But the most likely outcomes aren't always the best betting opportunities.
Start your free 3-day trial of Dimers Pro to unlock today's best bets and complete betting analysis for this matchup.
Responsible gambling
Dimers' predictions and betting insights are designed to help inform your betting decisions. If you're betting on Santos Laguna vs. San Luis, always gamble responsibly and within your means. For support, you can visit our responsible gambling resources.
