Panthers vs. Senators Prediction, Picks & Odds
Moneyline
- Panthers
- Senators
- Sam Reinhart36.0%
- Brady Tkachuk32.3%
- Carter Verhaeghe30.0%
- Matthew Tkachuk
- Sam Bennett
- Tim Stutzle36.0%
- Drake Batherson34.8%
- Dylan Cozens25.9%
- Shane Pinto
- Fabian Zetterlund
Panthers vs. Senators prediction & analysis
Game overview: NHL Wednesday
- Teams: Florida Panthers vs. Ottawa Senators
- Date: Wednesday, October 21, 2026
- Puck drop: 7:30PM ET
- Venue: Canadian Tire Centre
Current betting odds
- Puck line: Panthers (-1.5, +230), Senators (+1.5, -265)
- Moneyline: Panthers -102, Senators +100
- Total (Over/Under): 5.5 goals (-113/+108)
Dimers’ win probabilities
- Panthers: 48.0%
- Senators: 52.0%
Our NHL win probabilities come from a machine learning model that assesses each team’s offensive and defensive performance, calculating multiple factors and accounting for OT and shootout chances.
It draws from these projections to forecast probabilities for the moneyline, puck line, and total goals.
Panthers vs. Senators player props & projections
Our highest anytime goalscorer probabilities for this game are:
- Sam Reinhart, Panthers: 36.6%
- Brady Tkachuk, Panthers: 32.8%
- Tim Stutzle, Senators: 36.9%
- Drake Batherson, Senators: 34.1%
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Our Prediction: Who Wins?
After extensive simulations, our model gives the Panthers a win probability of 48.0%, while the Senators have a win probability of 52.0%.
Summary
According to our analysis, the Senators are more likely to beat the Panthers in the NHL game at Canadian Tire Centre on Wednesday.
That is the straight-up read. Whether either side is worth backing depends on the price, which is what our betting model rates.
Responsible gambling
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