Titans vs. Colts Prediction: Indianapolis Predicted to Win in NFL Week 16 [2024]

The Indianapolis Colts and Tennessee Titans will meet in Week 16 of the NFL season at Lucas Oil Stadium on Sunday, starting at 1:00PM ET.

Based on the latest simulation results, Dimers' proven NFL model (see Dimers Pro for full access) predicts the Colts as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Tennessee-Indianapolis game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Colts with a win probability of 63%, while the Titans have 37%."

This updated Titans vs. Colts betting preview builds on my early Titans vs. Colts prediction that I released at the start of the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Titans vs. Colts predictions page.

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Titans vs. Colts Game-Day Updates and Essential Details

The NFL Week 16 matchup between the Colts and Titans at Lucas Oil Stadium is scheduled to start at 1:00PM ET.

• Who: Tennessee Titans vs. Indianapolis Colts
• Date: Sunday, December 22, 2024
• Time: 1:00PM ET/10:00AM PT
• Venue: Lucas Oil Stadium
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Colts and Titans gear at Fanatics

Dimers.com's in-depth preview of this week's Titans vs. Colts matchup includes our prediction, picks and the latest betting odds.

Before making any Tennessee vs. Indianapolis picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

Titans vs. Colts Predictions

Using powerful machine learning and data, we have simulated the outcome of Sunday's NFL matchup between the Titans and Colts 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the Colts a 63% chance of defeating the Titans in Week 16 of the NFL season. Our predicted final score has the Colts winning 23-19.

According to our model, the Titans (+4) have a 52% chance of covering the spread, while the 42.5-point over/under has a 51% chance of going over.

Along with our Titans vs. Colts predictions, we've also got the following locked and loaded for today’s action:

• NFL Best Bets for Week 16
• NFL Player Props for Week 16
• Anytime TD Scorer Predictions for Week 16

Titans vs. Colts Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	Titans	Colts
Spread	+4 (-108)	-4 (-105)
Moneyline	+172	-190
Total	o42.5 (-110)	u42.5 (-105)

All odds are correct at the time of publication and are subject to change.

Titans vs. Colts Picks

Our model's strongest edge in today's Titans vs. Colts matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Titans vs. Colts TD Scorers

Who will score the first touchdown in Titans vs. Colts?

According to our model, Indianapolis' Jonathan Taylor is most likely to score the first TD in Titans vs. Colts.

Our projections give Taylor a 14.2% chance of getting in for six first at Lucas Oil Stadium, while the Colts RB is a 53.8% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

Tennessee Titans

Player	First TD Probability
Tony Pollard	10.6%
Calvin Ridley	8.9%
Tyjae Spears	7.6%

Indianapolis Colts

Player	First TD Probability
Jonathan Taylor	14.2%
Anthony Richardson	12.2%
Josh Downs	7.5%

Anytime Touchdown Scorer Predictions

Tennessee Titans

Player	Anytime TD Probability
Tony Pollard	41.9%
Calvin Ridley	37.4%
Tyjae Spears	32.0%

Indianapolis Colts

Player	Anytime TD Probability
Jonathan Taylor	53.8%
Anthony Richardson	46.7%
Josh Downs	31.6%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 16 touchdown scorer predictions

Titans vs Colts Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Titans and Colts. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Titans-Colts page now to access every player prop projection.

Titans vs. Colts Quarterbacks

Of the starting quarterbacks, the Titans' Mason Rudolph is projected to throw for more yards than the Colts' Anthony Richardson.

Titans Rushing

Tony Pollard, Tyjae Spears and Mason Rudolph are projected to be the leading rushers for the Titans.

Player	Position
Tony Pollard	RB
Tyjae Spears	RB
Mason Rudolph	QB

Colts Rushing

Jonathan Taylor, Anthony Richardson and Trey Sermon are expected to lead the Colts in rushing yards.

Player	Position
Jonathan Taylor	RB
Anthony Richardson	QB
Trey Sermon	RB

Titans Receiving

Calvin Ridley, Nick Westbrook-Ikhine, Chigoziem Okonkwo, Tony Pollard and Tyjae Spears are projected to top the receiving yards for the Titans.

Player	Position
Calvin Ridley	WR
Nick Westbrook-Ikhine	WR
Chigoziem Okonkwo	TE
Tony Pollard	RB
Tyjae Spears	RB

Colts Receiving

Michael Pittman, Josh Downs, Adonai Mitchell, Jonathan Taylor and Kylen Granson are projected to lead the Colts in receiving yards.

Player	Position
Michael Pittman	WR
Josh Downs	WR
Adonai Mitchell	WR
Jonathan Taylor	RB
Kylen Granson	TE

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Conclusion

We predict the Colts, with a 63% win probability, will likely beat the Titans in Week 16 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Titans vs. Colts insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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