Penrith Panthers vs. Sydney Roosters prediction: Why Panthers are favored to win NRL Finals week one matchup [9/13/2026]

The Penrith Panthers will face the Sydney Roosters in National Rugby League (NRL) action at Panthers Stadium on Sunday, beginning at 2:05 AM ET.

Dimers' advanced NRL model projects the Panthers as the most likely winner in this Roosters vs. Panthers prediction.

This article offers a closer look at Sunday's matchup, including best bets and picks.

Panthers vs. Roosters prediction and odds

Using powerful machine learning and statistical analysis, we have re-simulated the result of Sunday's NRL game between the Roosters and Panthers, forming part of our NRL predictions coverage.

Our independent predictive model gives the Panthers a 75.4% chance of defeating the Roosters. According to our model, the Panthers (-8.5) have a 54.5% chance of covering the spread, while the over/under total of 42.5 points has a 54.8% chance of going over.

Latest betting odds

We have researched the best NRL odds in America for this game, which are listed here:

• Moneyline: Roosters +205, Panthers -278
• Total: Over/Under 42.5 (-112/-114)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Panthers -8.5 @ -105 via DraftKings
• Moneyline: Panthers @ -278 via BetRivers
• Total: Over 42.5 @ -112 via BetRivers

According to our NRL best bets, the top play to make on this game is Panthers -8.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Sunday's Australian rugby league matchup between the Panthers and Roosters at Panthers Stadium is scheduled to commence at 2:05 AM ET.

• Who: Sydney Roosters vs. Penrith Panthers
• Date: Sunday, September 13, 2026
• Time: 2:05 AM ET/11:05PM PT
• Venue: Panthers Stadium

The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.

Conclusion

We predict the Panthers, with a 75.4% win probability, will likely beat the Roosters in Sunday's NRL matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary NRL prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.