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Trail Blazers vs. Spurs prediction: San Antonio favored to win Wednesday's NBA game [4/8/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Portland Trail Blazers vs San Antonio Spurs predictions for NBA Wednesday.
The San Antonio Spurs will take on the Portland Trail Blazers in NBA action at Frost Bank Center on Wednesday, commencing at 9:30 PM ET.
Based on the latest simulation results and today’s injury reports, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Trail Blazers vs. Spurs game.
This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature stars like De'Aaron Fox, Keldon Johnson and Dylan Harper, while the Trail Blazers will be led by Deni Avdija, Jrue Holiday and Scoot Henderson.
This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Blazers vs. Spurs prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Trail Blazers and Spurs, forming part of our NBA predictions coverage.
Our famous predictive model currently gives the Spurs a 64% chance of defeating the Trail Blazers. Our predicted final score has the Spurs winning 116-112.
According to our model, the Spurs (-3.5) have a 52% chance of covering the spread, while the 229-point over/under has a 51% chance of staying under.
Trail Blazers vs. Spurs odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Trail Blazers | Spurs |
|---|---|---|
| Spread | +3.5 (-114) | -3.5 (-102) |
| Moneyline | +140 | -155 |
| Total | o229 (-110) | u229 (-110) |
All odds are correct at the time of publication and are subject to change.
Trail Blazers vs. Spurs picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Spurs -3.5 | -102 |
| Moneyline | Spurs | -155 |
| Total | Under 229 | -110 |
According to our best NBA bets for Wednesday, the top play to make on this game is Spurs to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Trail Blazers vs. Spurs player props
NBA prop bets are an exciting way to wager on Wednesday's Portland vs. San Antonio game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Frost Bank Center.
Deni Avdija is expected to lead the Trail Blazers with 26 points, 8 rebounds and 7 assists, while De'Aaron Fox is projected to have 18 points, 3 rebounds and 6 assists for the Spurs.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Trail Blazers prediction
Our model's projected player stats for the Trail Blazers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Deni Avdija | 26 | 8 | 7 | 2 | 52 |
| Jrue Holiday | 18 | 5 | 6 | 3 | 39 |
| Scoot Henderson | 14 | 3 | 4 | 2 | 29 |
| Toumani Camara | 14 | 5 | 2 | 3 | 29 |
| Donovan Clingan | 14 | 11 | 4 | 1 | 39 |
Spurs prediction
Projected points, rebounds, assists and three-pointers made for the Spurs:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| De'Aaron Fox | 18 | 3 | 6 | 2 | 36 |
| Keldon Johnson | 16 | 6 | 2 | 2 | 29 |
| Dylan Harper | 15 | 4 | 5 | 1 | 33 |
| Devin Vassell | 14 | 4 | 3 | 2 | 29 |
| J. Champagnie | 13 | 6 | 2 | 3 | 28 |
Blazers vs. Spurs game-day updates and essential details
Wednesday's game between the Spurs and Trail Blazers at Frost Bank Center is scheduled to commence at 9:30 PM ET.
- Who: Portland Trail Blazers vs. San Antonio Spurs
- Date: Wednesday, April 8, 2026
- Time: 9:30 PM ET/6:30PM PT
- Venue: Frost Bank Center
Conclusion
We predict the Spurs, with a 64% win probability, will likely beat the Trail Blazers on Wednesday, with Deni Avdija projected for a game-high 52 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Trail Blazers vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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