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76ers vs. Timberwolves prediction: Minnesota to win, Anthony Edwards projected for big game in Sunday's NBA matchup [2/22/2026]

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Written by Dave Garofolo

Get Philadelphia 76ers vs Minnesota Timberwolves predictions for NBA Sunday.

Philadelphia 76ers-Minnesota Timberwolves Predictions and Game Preview.
Philadelphia 76ers vs. Minnesota Timberwolves NBA prediction for Sunday, February 22, 2026.

NBA action continues on Sunday at 7:00 PM ET as the Philadelphia 76ers take on the favored Minnesota Timberwolves at Target Center.

Based on the latest simulation results and today’s injury reports, Dimers' proven NBA model predicts the Timberwolves as the most likely winner of the 76ers vs. Timberwolves game.

This prediction follows the latest NBA Injury Report, which suggests the Timberwolves lineup will feature stars like Anthony Edwards, Julius Randle and Naz Reid, while the 76ers will rely on Tyrese Maxey, Kelly Oubre and VJ Edgecombe.

This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Sixers vs. Sixers prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Sunday's NBA matchup between the 76ers and Timberwolves 10,000 times as part of our NBA predictions coverage.

Our famous predictive model gives the Timberwolves a 77% chance of beating the 76ers. Our predicted final score has the Timberwolves winning 123-114.

According to our model, the 76ers (+8.5) have a 54% chance of covering the spread, while the over/under total of 238.5 points has a 53% chance of staying under.

 

76ers vs. Timberwolves odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type 76ers Timberwolves
Spread +8.5 (-105) -8.5 (-110)
Moneyline +300 -345
Total o238.5 (-112) u238.5 (-108)

All odds are correct at the time of publication and are subject to change.

76ers vs. Timberwolves picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread 76ers +8.5 -105
Moneyline 76ers +300
Total Under 238.5 -108

According to our best NBA bets for Sunday, the top play to make on this game is 76ers +8.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

76ers vs. Timberwolves player props

NBA prop bets are a popular way to wager on Sunday's 76ers vs. Timberwolves game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Target Center.

Tyrese Maxey is expected to lead the 76ers with 27 points, 4 rebounds and 7 assists, while Anthony Edwards is projected to have 31 points, 6 rebounds and 4 assists for the Timberwolves.

Anthony Edwards 2026.
Anthony Edwards is projected to score 31 points tonight.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

76ers prediction

Our model's projected player stats for the 76ers are:

Player PTS REB AST 3PM DFS
Tyrese Maxey 27 4 7 3 49
Kelly Oubre 17 5 2 2 31
VJ Edgecombe 15 5 4 2 33
Quentin Grimes 11 3 3 2 24
Dominick Barlow 10 5 1 0 22

Timberwolves prediction

Projected points, rebounds, assists and three-pointers made for the Timberwolves:

Player PTS REB AST 3PM DFS
Anthony Edwards 31 6 4 3 52
Julius Randle 22 7 6 1 45
Naz Reid 16 8 3 3 38
Jaden McDaniels 15 5 4 1 33
Ayo Dosunmu 15 3 4 2 29

Sixers vs. Wolves game-day updates and essential details

Sunday's action between the Timberwolves and 76ers at Target Center is scheduled to start at 7:00 PM ET.

Conclusion

We predict the Timberwolves, with a 77% win probability, will likely beat the 76ers on Sunday, with Anthony Edwards projected for a game-high 52 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate 76ers vs. Timberwolves insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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