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Northwestern vs. Illinois prediction: Why Illinois is favored to win in college football Week 14, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Northwestern vs Illinois predictions for college football Saturday.
Illinois and Northwestern will lock horns in Week 14 college football action at Gies Memorial Stadium on Saturday, beginning at 7:30PM ET.
Based on updated simulation results, Dimers' advanced college football model predicts Illinois as the most likely winner of the Northwestern vs. Illinois game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Northwestern vs. Illinois prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the result of Northwestern vs. Illinois 10,000 times as part of our college football predictions coverage.
Our independent predictive model currently gives Illinois a 68% chance of beating Northwestern. Our predicted final score has Illinois winning 26-20.
According to our model, Northwestern (+7) has a 53% chance of covering the spread, while the 44.5-point over/under has a 55% chance of staying under.
Northwestern vs. Illinois odds
We have sourced the best college football odds in America for this game, which are listed here:
| Bet Type | Northwestern | Illinois |
|---|---|---|
| Spread | +7 (-110) | -7 (-108) |
| Moneyline | +225 | -250 |
| Total | o44.5 (-102) | u44.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Northwestern vs. Illinois picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Northwestern +7 | -110 |
| Moneyline | Northwestern | +225 |
| Total | Under 44.5 | -110 |
According to our college football best bets, the top play to make on this game is Under 44.5 total points.
Northwestern vs. Illinois game-day updates and essential details
Saturday's college football game between Illinois and Northwestern at Gies Memorial Stadium is scheduled to commence at 7:30PM ET.
- Who: Northwestern vs. Illinois
- Date: Saturday, November 29, 2025
- Time: 7:30PM ET/4:30PM PT
- Venue: Gies Memorial Stadium
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Conclusion
We predict Illinois, with a 68% win probability, will likely beat Northwestern on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Northwestern vs. Illinois insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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