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Grizzlies vs. Timberwolves prediction: Minnesota to win, Anthony Edwards projected for big game in Wednesday's NBA matchup [12/17/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Memphis Grizzlies vs Minnesota Timberwolves predictions for NBA Wednesday.
The Minnesota Timberwolves will take on the Memphis Grizzlies in NBA action at Target Center on Wednesday, starting at 8:00 PM ET.
Based on updated simulation results and today’s injury news, Dimers' advanced NBA model projects the Timberwolves as the most likely winner of the Grizzlies vs. Timberwolves game.
This prediction follows the latest NBA Injury Report, which suggests the Timberwolves lineup will feature players like Anthony Edwards, Julius Randle and Jaden McDaniels, while the Grizzlies will rely on Jaren Jackson, Ja Morant and Santi Aldama.
This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Grizzlies vs. Wolves prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the outcome of Wednesday's NBA matchup between the Grizzlies and Timberwolves 10,000 times as part of our NBA predictions coverage.
Our independent predictive model gives the Timberwolves a 72% chance of beating the Grizzlies. Our predicted final score has the Timberwolves winning 118-112.
According to our model, the Grizzlies (+7.5) have a 53% chance of covering the spread, while the over/under total of 230.5 points has an equal 50-50 chance of hitting.
Grizzlies vs. Timberwolves odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Grizzlies | Timberwolves |
|---|---|---|
| Spread | +7.5 (-110) | -7.5 (-108) |
| Moneyline | +245 | -298 |
| Total | o230.5 (-108) | u230.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Grizzlies vs. Timberwolves picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Grizzlies +7.5 | -110 |
| Moneyline | Grizzlies | +245 |
| Total | Over 230.5 | -108 |
According to our best NBA bets for Wednesday, the top play to make on this game is Grizzlies +7.5 at the spread.
Grizzlies vs. Timberwolves player props
NBA prop bets are a great way to wager on the Memphis vs. Minnesota matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Target Center.
Jaren Jackson is expected to lead the Grizzlies with 19 points, 5 rebounds and 2 assists, while Anthony Edwards is projected to have 27 points, 5 rebounds and 5 assists for the Timberwolves.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Grizzlies prediction
Our model's projected player stats for the Grizzlies are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaren Jackson | 19 | 5 | 2 | 2 | 34 |
| Ja Morant | 18 | 3 | 6 | 1 | 36 |
| Santi Aldama | 14 | 6 | 3 | 2 | 32 |
| Jaylen Wells | 14 | 4 | 2 | 2 | 25 |
| Cedric Coward | 13 | 6 | 3 | 1 | 29 |
Timberwolves prediction
Projected points, rebounds, assists and three-pointers made for the Timberwolves:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Anthony Edwards | 27 | 5 | 5 | 4 | 47 |
| Julius Randle | 23 | 7 | 5 | 2 | 45 |
| Jaden McDaniels | 16 | 5 | 3 | 2 | 32 |
| D. DiVincenzo | 14 | 4 | 4 | 3 | 31 |
| Naz Reid | 13 | 6 | 3 | 2 | 31 |
Grizzlies vs. Wolves game-day updates and essential details
Wednesday's matchup between the Timberwolves and Grizzlies at Target Center is scheduled to commence at 8:00 PM ET.
- Who: Memphis Grizzlies vs. Minnesota Timberwolves
- Date: Wednesday, December 17, 2025
- Time: 8:00 PM ET/5:00PM PT
- Venue: Target Center
Conclusion
We predict the Timberwolves, with a 72% win probability, will likely beat the Grizzlies on Wednesday, with Anthony Edwards projected for a game-high 47 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Timberwolves insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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