Grizzlies vs. Clippers prediction: Clippers favored to win Black Friday NBA matchup [11/28/2025]

The Los Angeles Clippers will take on the Memphis Grizzlies in NBA Cup Black Friday action at Intuit Dome on Friday, beginning at 10:00PM ET.

Based on the latest simulation results and today’s injury reports, Dimers' proven NBA model predicts the Clippers as the most likely winner of the Grizzlies vs. Clippers game.

This prediction follows the latest NBA Injury Report, which suggests the Clippers lineup will feature players like James Harden, Kawhi Leonard and Ivica Zubac, while the Grizzlies will rely on Jaren Jackson, Cedric Coward and Santi Aldama.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Grizzlies vs. Clippers prediction: Who will win NBA Cup game?

As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Friday's clash between the Grizzlies and Clippers.

Our famous predictive model gives the Clippers a 72% chance of defeating the Grizzlies. Our predicted final score has the Clippers winning 115-109.

According to our model, the Grizzlies (+6.5) have a 52% chance of covering the spread, while the over/under total of 224.5 points has an equal 50-50 chance of hitting.

Grizzlies vs. Clippers odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Grizzlies vs. Clippers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Friday, the top play to make on this game is Grizzlies +6.5 at the spread.

Grizzlies vs. Clippers player props

Looking for Grizzlies vs. Clippers NBA player props? We have crunched the numbers to project how each team's leading players will perform at Intuit Dome.

Jaren Jackson is expected to lead the Grizzlies with 21 points, 5 rebounds and 2 assists, while James Harden is projected to have 25 points, 6 rebounds and 9 assists for the Clippers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Grizzlies prediction

Our model's projected player stats for the Grizzlies are:

Clippers prediction

Projected points, rebounds, assists and three-pointers made for the Clippers:

Grizzlies vs. Clippers game-day updates and essential details

Friday's game between the Clippers and Grizzlies at Intuit Dome is scheduled to commence at 10:00PM ET.

• Who: Memphis Grizzlies vs. Los Angeles Clippers
• Date: Friday, November 28, 2025 (Black Friday)
• Time: 10:00PM ET/7:00PM PT
• Venue: Intuit Dome
• Tournament details: 2025 Emirates NBA Cup

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Conclusion

We predict the Clippers, with a 72% win probability, will likely beat the Grizzlies on Black Friday, with James Harden projected for a game-high 54 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Clippers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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