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LSU vs. Oklahoma prediction: Oklahoma favored to win in college football Week 14, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get LSU vs Oklahoma predictions for college football Saturday.
Oklahoma and LSU will meet in Week 14 college football action at Gaylord Family Oklahoma Memorial Stadium on Saturday, beginning at 3:30PM ET.
Based on the latest simulation results, Dimers' proven college football model projects Oklahoma as the most likely winner of the LSU vs. Oklahoma game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
LSU vs. Oklahoma prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the outcome of LSU vs. Oklahoma 10,000 times as part of our college football predictions coverage.
Our independent predictive model gives Oklahoma an 86% chance of beating LSU. Our predicted final score has Oklahoma winning 23-12.
According to our model, LSU (+11.5) has a 51% chance of covering the spread, while the 36.5-point over/under has a 51% chance of staying under.
LSU vs. Oklahoma odds
We have sourced the best college football odds in America for this game, which are listed here:
| Bet Type | LSU | Oklahoma |
|---|---|---|
| Spread | +11.5 (-106) | -11.5 (-114) |
| Moneyline | +410 | -500 |
| Total | o36.5 (-106) | u36.5 (-112) |
All odds are correct at the time of publication and are subject to change.
LSU vs. Oklahoma picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | LSU +11.5 | -106 |
| Moneyline | Oklahoma | -500 |
| Total | Under 36.5 | -112 |
According to our college football best bets, the top play to make on this game is Oklahoma to win.
LSU vs. Oklahoma game-day updates and essential details
Saturday's college football game between Oklahoma and LSU at Gaylord Family Oklahoma Memorial Stadium is scheduled to start at 3:30PM ET.
- Who: LSU vs. Oklahoma
- Date: Saturday, November 29, 2025
- Time: 3:30PM ET/12:30PM PT
- Venue: Gaylord Family Oklahoma Memorial Stadium
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Conclusion
We predict Oklahoma, with an 86% win probability, will likely beat LSU on Saturday.
AI and automation have enhanced this article to quickly deliver accurate LSU vs. Oklahoma insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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