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Lakers vs. Spurs prediction: San Antonio to win, Luka Doncic projected for 36 points in Wednesday's NBA game [1/7/2026]

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Written by Jason Bevilacqua

Get Los Angeles Lakers vs San Antonio Spurs predictions for NBA Wednesday.

Los Angeles Lakers-San Antonio Spurs Predictions and Game Preview.
Los Angeles Lakers vs. San Antonio Spurs NBA prediction for Wednesday, January 7, 2026.

The San Antonio Spurs and Los Angeles Lakers will lock horns in NBA action at Frost Bank Center on Wednesday, starting at 9:30 PM ET.

Based on the latest simulation results and today’s injury news, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Lakers vs. Spurs game.

This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like De'Aaron Fox, Stephon Castle and Victor Wembanyama, while the Lakers will look to Luka Doncic, Deandre Ayton and Jake LaRavia.

LeBron James will miss the game though with the superstar out for this one.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Lakers vs. Spurs prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Lakers and Spurs 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Spurs a 74% chance of beating the Lakers. Our predicted final score has the Spurs winning 120-112.

According to our model, the Lakers (+8.5) have a 54% chance of covering the spread, while the 233.5-point over/under has a 51% chance of staying under.

 

Lakers vs. Spurs odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Lakers Spurs
Spread +8.5 (-105) -8.5 (-112)
Moneyline +260 -295
Total o233.5 (-110) u233.5 (-106)

All odds are correct at the time of publication and are subject to change.

Lakers vs. Spurs picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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