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Iowa vs. Nebraska prediction: Iowa favored to win Black Friday College Football matchup, 2025

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Written by Mac Douglass

Get Iowa vs Nebraska predictions for college football Friday.

Iowa-Nebraska Predictions and Game Preview.
Iowa vs. Nebraska college football gameday prediction for Friday, November 28, 2025.

Nebraska and Iowa will meet in Week 14 college football action at Memorial Stadium on Friday, starting at 12:00PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts Iowa as the most likely winner of the Iowa vs. Nebraska game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Iowa vs. Nebraska prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Iowa vs. Nebraska 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Iowa a 69% chance of beating Nebraska. Our predicted final score has Iowa winning 24-18.

According to our model, the bookies have got it right, and Iowa and Nebraska each have a 50% chance of covering the spread, while the over/under total of 39.5 points has a 60% chance of staying under.

 

Iowa vs. Nebraska odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type Iowa Nebraska
Spread -5.5 (-110) +5.5 (-105)
Moneyline -205 +195
Total o39.5 (-105) u39.5 (-110)

All odds are correct at the time of publication and are subject to change.

Iowa vs. Nebraska picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Nebraska +5.5 -105
Moneyline Iowa -205
Total Under 39.5 -110

According to our college football best bets, the top play to make on this game is Under 39.5 total points.

 

Iowa vs. Nebraska game-day updates and essential details

Friday's college football action between Nebraska and Iowa at Memorial Stadium is scheduled to start at 12:00PM ET.

  • Who: Iowa vs. Nebraska
  • Date: Friday, November 28, 2025 (Black Friday)
  • Time: 12:00PM ET/9:00AM PT
  • Venue: Memorial Stadium

 

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To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that secures the best opening offer in the game. Don't miss out!

Conclusion

We predict Iowa, with a 69% win probability, will likely beat Nebraska on Black Friday.

AI and automation have enhanced this article to quickly deliver accurate Iowa vs. Nebraska insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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