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Bulls vs. Pistons prediction: Detroit favored to win Wednesday's NBA matchup [1/7/2026]

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Written by Ryan Leaver

Get Chicago Bulls vs Detroit Pistons predictions for NBA Wednesday.

Chicago Bulls-Detroit Pistons Predictions and Game Preview.
Chicago Bulls vs. Detroit Pistons NBA prediction for Wednesday, January 7, 2026.

The Detroit Pistons will face the Chicago Bulls in NBA action at Little Caesars Arena on Wednesday, beginning at 7:00 PM ET.

Based on the latest simulation results and today’s injury updates, Dimers' advanced NBA model projects the Pistons as the most likely winner of the Bulls vs. Pistons game.

This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature stars like Cade Cunningham, Paul Reed and Isaiah Stewart, while the Bulls will be led by Nikola Vucevic, Matas Buzelis and Ayo Dosunmu.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Bulls vs. Pistons prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's NBA matchup between the Bulls and Pistons 10,000 times as part of our NBA predictions coverage.

Our famous predictive model gives the Pistons a 72% chance of defeating the Bulls. Our predicted final score has the Pistons winning 117-110.

According to our model, the Bulls (+7.5) have a 55% chance of covering the spread, while the over/under total of 227.5 points has an equal 50-50 chance of hitting.

 

Bulls vs. Pistons odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Bulls Pistons
Spread +7.5 (+100) -7.5 (-118)
Moneyline +265 -325
Total o227.5 (-108) u227.5 (-110)

All odds are correct at the time of publication and are subject to change.

Bulls vs. Pistons picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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