NY Red Bulls vs. St Louis City prediction, odds, MLS picks [9/30/2026]

The NY Red Bulls will take on St Louis City in MLS action at Sports Illustrated Stadium on Wednesday, starting at 7:30 PM ET.

Dimers' proven MLS model projects St Louis City as the most likely winner in this NY Red Bulls vs. St Louis City prediction.

This article offers a closer look at Wednesday's match, including best bets and picks.

NY Red Bulls vs. St Louis City prediction and odds

Using innovative machine learning and data, we have re-simulated the result of Wednesday's MLS game between NY Red Bulls and St Louis City, forming part of our MLS predictions coverage.

Our leading predictive model suggests a 29.9% chance of NY Red Bulls winning, a 47.2% chance for St Louis City, and a 23.0% chance of a draw. Additionally, the 2.5-goal over/under has a 61.8% chance of going over., according to our model.

Latest betting odds

We have sourced the best MLS odds in America for this game, which are listed here:

• Moneyline: St Louis City -104, NY Red Bulls +280
• Total Goals: Over/Under 2.5 (-194/+186)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: NY Red Bulls @ +280 via Fanatics
• Total Goals: Under 2.5 @ +186 via Polymarket

According to our MLS best bets, the top play to make on this game is NY Red Bulls to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score projections

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

• NY Red Bulls 1-1 St Louis City (10.3% probability)
• NY Red Bulls 1-2 St Louis City (9.3%)
• NY Red Bulls 0-1 St Louis City (7.4%)

These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score can differ from our predicted winner.

Game info & kickoff details

Wednesday's MLS matchup between NY Red Bulls and St Louis City in MLS at Sports Illustrated Stadium is scheduled to commence at 7:30 PM ET.

• Who: NY Red Bulls vs. St Louis City
• Date: Wednesday, September 30, 2026
• Time: 7:30 PM ET/4:30PM PT
• Venue: Sports Illustrated Stadium

Conclusion

According to our computer model, NY Red Bulls have a 29.9% win probability on Wednesday, St Louis City has a 47.2% win probability, and there is a 23.0% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLS prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.