Columbus Crew vs. Inter Miami prediction, odds, MLS picks [9/27/2026]

Columbus will take on Miami in MLS action at ScottsMiracle-Gro Field on Sunday, commencing at 7:00 PM ET.

Dimers' advanced MLS model projects Miami as the most likely winner in this Columbus vs. Miami prediction.

This article offers further insights into Sunday's match, including best bets and picks.

Columbus Crew vs. Inter Miami prediction and odds

Using trusted machine learning and data, we have re-simulated the result of Sunday's MLS matchup between Columbus and Miami, forming part of our MLS predictions coverage.

Our leading predictive model currently suggests a 37.4% chance of Columbus winning, a 41.0% chance for Miami, and a 21.6% chance of a draw. Additionally, the over/under total of 2.5 goals has a 71.6% chance of going over., according to our model.

Latest betting odds

We have researched the best MLS odds in America for this game, which are listed here:

• Moneyline: Miami +133, Columbus +194
• Total Goals: Over/Under 2.5 (-245/+235)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Columbus @ +194 via Polymarket
• Total Goals: Over 2.5 @ -245 via Polymarket

According to our MLS best bets, the top play to make on this game is Columbus to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score projections

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

• Columbus 1-1 Miami (8.4% probability)
• Columbus 1-2 Miami (8%)
• Columbus 2-1 Miami (7.6%)

These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score can differ from our predicted winner.

Game info & kickoff details

Sunday's MLS matchup between Columbus and Miami in MLS at ScottsMiracle-Gro Field is scheduled to begin at 7:00 PM ET.

• Who: Columbus Crew vs. Inter Miami
• Date: Sunday, September 27, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: ScottsMiracle-Gro Field

Conclusion

According to our computer model, Columbus has a 37.4% win probability on Sunday, Miami has a 41.0% win probability, and there is a 21.6% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLS prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.