Cardinals vs. Marlins Prediction, Picks and Odds

Our detailed prediction and analysis for the Cardinals vs. Marlins MLB game on April 21, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
FINAL
MLB
FINAL
MLB sport icon
MLB
Cardinals
Dustin May 2-2, 6.98 ERA
5
3
loanDepot park
Marlins
Chris Paddack 0-3, 5.59 ERA
loanDepot park
1 2 3 4 5 6 7 8 9 RHE
Cardinals
1 0 1 2 1 0 0 0 0 5 10 1
Marlins
1 0 0 0 0 0 0 2 0 3 8 0
Live Probabilities
Win %
  • Cardinals
    100%
  • Marlins
    0%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Xavier Edwards lines out to left field to Nathan Church.
Quick Box Score
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Wetherholt 2B4210012.2500.900
2 I. Herrera DH5020002.4000.800
3 A. Burleson 1B4122001.5001.250
4 J. Walker RF4000002.0000.000
5 N. Gorman 3B4011002.2500.500
6 M. Winn SS4120000.5001.250
7 N. Church LF4122100.5001.750
8 P. Pagés C4000002.0000.000
9 V. Scott CF3000011.0000.250
Marlins Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Marsee CF4131100.7502.300
2 K. Stowers RF4000011.0000.200
3 O. Lopez SS5000001.0000.000
4 X. Edwards 2B4120010.5001.100
5 L. Hicks C3100010.0000.250
6 A. Ramírez DH4000002.0000.000
7 J. Sanoja 3B0000010.0001.000
8 H. Hernández LF10120001.0002.000
9 C. Norby 1B4010002.2500.500

Cardinals vs. Marlins: Detailed Breakdown

Matchup Overview

  • Teams: Cardinals vs. Marlins
  • Date: Tuesday, April 21, 2026
  • Time: 6:40 PM ET
  • Venue: loanDepot park

Current Betting Odds

  • Spread: Marlins favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: Cardinals 48¢, Marlins 53¢

Dimers' Win Probabilities

  • Cardinals: 47%
  • Marlins: 53%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cardinals a win probability of 47%, while the Marlins have a win probability of 53%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Marlins are more likely to beat the Cardinals in the MLB game at loanDepot park on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cardinals vs. Marlins predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.