Cubs vs. Reds: MLB Prediction & Analysis

Our detailed prediction and analysis for the Cubs vs. Reds MLB game on Friday, September 18, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
FINAL
MLB
FINAL
MLB sport icon
MLB
Cubs
Clay Holmes 6-7, 2.85 ERA
4
6
Great American Ball Park
Reds
Chase Burns 15-3, 2.80 ERA
Great American Ball Park
1 2 3 4 5 6 7 8 9 RHE
Cubs
0 1 1 2 0 0 0 0 0 4 9 1
Reds
2 0 1 0 0 3 0 0 X 6 8 0
Live Probabilities
Win %
  • Cubs
    0%
  • Reds
    100%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Alex Bregman flies out to deep center field to Carlos Jorge.
Quick Box Score
Cubs Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 P. Crow-Armstrong CF5000003.0000.000
2 S. Suzuki RF5012003.2000.400
3 M. Busch 1B3000021.0000.400
4 A. Bregman 3B5000000.0000.000
5 I. Happ LF4111101.2501.250
6 N. Hoerner 2B4110000.2500.500
7 M. Conforto DH4030000.7501.500
8 C. Kelly C21210101.0002.000
9 D. Swanson SS3110011.3330.833
Reds Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 C. Jorge CF3210010.3331.500
2 E. De La Cruz SS22200201.0002.000
3 S. Stewart 1B3011000.3330.583
4 T. Stephenson DH3011012.3330.833
5 J. Bleday RF3110011.3330.833
6 K. Hayes 3B0000000.0000.000
7 T. Friedl LF0000000.0000.000
8 J. Trevino C4012001.2500.500
9 M. McLain 2B3000000.0000.000

Cubs vs. Reds: Detailed Breakdown

Matchup overview: MLB Friday

  • Teams: CHI Cubs Cubs vs. Cincinnati Reds
  • Date: Friday, September 18, 2026
  • Time: 6:40PM ET
  • Venue: Great American Ball Park

Current betting odds

  • Spread: Cubs (-1.5, +122), Reds (+1.5, -125)
  • Moneyline: Cubs -138, Reds +133
  • Total (Over/Under): 8.5 runs (-104/+100)

Dimers’ win probabilities

  • Cubs: 54.1%
  • Reds: 45.9%

Dimers' predictive MLB model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Cubs a win probability of 54.1%, while the Reds have a win probability of 45.9%.

Summary

According to our analysis, the Cubs are more likely to beat the Reds in the MLB game at Great American Ball Park on Friday. Discover the best run line, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Cubs vs. Reds predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.