Athletics vs. Pirates Prediction, Picks and Odds

Our detailed prediction and analysis for the Athletics vs. Pirates MLB game on September 21, 2025 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
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MLB
Athletics
Mitch Spence 3-5, 4.48 ERA
0
11
Sep 21, 1:35 PM ET PNC Park
Pirates
Mike Burrows 2-4, 4.10 ERA
Sep 21, 1:35 PM ET PNC Park
1 2 3 4 5 6 7 8 9 RHE
Athletics
0 0 0 0 0 0 0 0 0 0 8 1
Pirates
2 2 0 3 3 0 0 1 X 11 15 0
Live Probabilities
Win %
  • Athletics
    0%
  • Pirates
    100%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Willie MacIver strikes out swinging.
Quick Box Score
Athletics Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 C. Thomas CF100000100.000
2 B. Rooker DH40200000.51.000
3 B. Harris 1B101000013.000
4 J. Bleday LF200000200.000
5 M. Muncy 3B000000000.000
6 C. Cortes RF40100000.250.500
7 D. Hernaiz SS400000100.000
8 W. MacIver C40100010.250.500
9 M. Schuemann 2B30100010.3330.666
Pirates Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 O. Cruz CF51120010.20.400
2 C. Devanney 3B000000000.000
3 A. Canario RF101000012.000
4 S. Horwitz 1B310102100.400
5 A. McCutchen DH41110110.250.650
6 N. Gonzales SS40110010.250.750
7 J. Suwinski LF41100010.250.750
8 J. Bart C424310013.000
9 N. Yorke 2B42100010.250.750

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Athletics vs. Pirates: Detailed Breakdown

Matchup Overview

  • Teams: Athletics vs. Pirates
  • Date: Sunday, September 21, 2025
  • Time: 1:35 PM ET
  • Venue: PNC Park

Current Betting Odds

  • Spread: Pirates favored at -1.5
  • Total (Over/Under): 8.5
  • Moneyline Odds: Athletics +105, Pirates -118

Dimers' Win Probabilities

  • Athletics: 48%
  • Pirates: 52%

Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Athletics a win probability of 48%, while the Pirates have a win probability of 52%. Discover the best spread, over/under, and moneyline odds for the game on this page.

Summary

According to our analysis, the Pirates are more likely to beat the Athletics in the MLB game at PNC Park on Sunday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Athletics vs. Pirates predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.