Dodgers vs. Twins prediction: Why Dodgers are favored to win Monday's MLB matchup [6/22/2026]

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Written by Jason Bevilacqua

Get Los Angeles Dodgers vs Minnesota Twins predictions for MLB Monday.

Los Angeles Dodgers-Minnesota Twins Predictions and Game Preview.
Los Angeles Dodgers vs. Minnesota Twins MLB prediction for Monday, June 22, 2026.

The Minnesota Twins will face the Los Angeles Dodgers in MLB action at Target Field on Monday, beginning at 7:40 PM ET.

The Twins will have Zebby Matthews (3-4, 4.78 ERA) as their starting pitcher, pitting him against Will Klein (2-2, 2.37 ERA) for the Dodgers.

Based on the latest simulations, Dimers' proven MLB model projects the Dodgers as the most likely winner of the Dodgers vs. Twins game.

This article offers a closer look at Monday's matchup, including best bets and picks.

Dodgers vs. Twins prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the result of Monday's MLB matchup between the Dodgers and Twins, forming part of our MLB predictions coverage.

Our famous predictive model gives the Dodgers a 56.3% chance of defeating the Twins.

According to our model, the Twins (+1.5) have a 54.9% chance of covering the run line, while the over/under total of 10 runs has a 54.3% chance of going over,.

 

Dodgers vs. Twins odds [6/22/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Twins
Run Line -1.5 (+106) +1.5 (-123)
Moneyline -148 +129
Total o10 (-111) u10 (-105)

All odds are correct at the time of publication and are subject to change.

Dodgers vs. Twins picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Twins +1.5 -123
Moneyline Twins +129
Total Over 10 -111

According to our MLB best bets, the top play to make on this game is Over 10 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Dodgers vs. Twins game-day updates and essential details

Monday's MLB matchup between the Twins and Dodgers at Target Field is scheduled to start at 7:40 PM ET.

Conclusion

We predict the Dodgers, with a 56.3% win probability, will likely beat the Twins in Monday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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