Sep 9, 2026
Cardinals vs. Giants prediction: St. Louis favored to win Wednesday's MLB matchup [9/9/2026]
Read Article Guardians vs. Orioles prediction: Baltimore favored to win Wednesday's MLB matchup [9/9/2026]
Updated: | First published:
Add Dimers on Google 
Written by Jason Bevilacqua, Head of Content and Communities
Dimers' simulation model projects a 50.2% win probability for the Orioles at Oriole Park at Camden Yards.
MLB action continues on Wednesday at 6:35 PM ET as the Cleveland Guardians lock horns with the Baltimore Orioles at Oriole Park at Camden Yards.
Shane Baz (5-15, 3.91 ERA) will start for the Orioles, pitting him against Foster Griffin (15-4, 3.26 ERA) for the Guardians.
Dimers' advanced MLB model gives the Orioles a slight edge with a 50.2% win probability over the Guardians.
This article offers a complete Guardians vs. Orioles prediction, including best bets and picks.
Guardians vs. Orioles prediction and odds
Using powerful machine learning and data, we have re-simulated the outcome of Wednesday's MLB game between the Guardians and Orioles, forming part of our MLB predictions coverage.
Our famous predictive model currently gives the Orioles a 50.2% chance of beating the Guardians.
According to our model, the Orioles (+1.5) have a 62.0% chance of covering the run line, while the over/under total of 8.5 runs has a 55.9% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Guardians -1.5 (+156) / Orioles +1.5 (-160)
- Moneyline: Guardians -104, Orioles +102
- Total: Over/Under 8.5 (-110/+108)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Orioles +1.5 @ -160 via FanDuel
- Moneyline: Orioles @ +102 via BetRivers
- Total: Over 8.5 @ -110 via BetRivers
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Wednesday's MLB matchup between the Orioles and Guardians at Oriole Park at Camden Yards is scheduled to begin at 6:35 PM ET.
- Who: Cleveland Guardians vs. Baltimore Orioles
- Date: Wednesday, September 9, 2026
- Time: 6:35 PM ET/3:35PM PT
- Venue: Oriole Park at Camden Yards
Conclusion
We predict the Orioles, with a 50.2% win probability, will likely beat the Guardians in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Lock in for all of NFL & College Football. Every plan unlocks every model, tool and insight, only the billing term changes.
MOST FLEXIBLE
Monthly billed monthly
$29.99
Month to month Pay as you go RECOMMENDED
6 Months one payment
$99.99 $149.99
6 months $16.67 per month Save $79.95 · 44% Early bird price BEST VALUE
Annual first year
$149.99 $199.99
12 months $12.50 per month Save $209.89 · 58% Early bird price Every plan includes
Full site access
iOS & Android app
AI bet assistant
Unlimited picks & predictions
Unlimited best bets & props
Unlimited player projections
Private Discord community
Cancel or pause anytime
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
Advertiser disclosure
