Reds vs. Cardinals prediction: St. Louis favored to win Sunday's MLB matchup [6/7/2026]
Get Cincinnati Reds vs St. Louis Cardinals predictions for MLB Sunday.

The St. Louis Cardinals and Cincinnati Reds are scheduled to meet in MLB action at Busch Stadium on Sunday, starting at 2:15 PM ET.
The Cardinals will start Michael McGreevy (3-5, 2.98 ERA), while the Reds are going with Rhett Lowder (3-3, 5.40 ERA).
Based on the latest simulations, Dimers' advanced MLB model predicts the Cardinals as the most likely winner of the Reds vs. Cardinals game.
This article offers further insights into Sunday's matchup, including best bets and picks.
Reds vs. Cardinals prediction: Who will win and cover?
Our independent predictive model currently gives the Cardinals a 57.3% chance of defeating the Reds.
According to our model, the Reds (+1.5) have a 58.7% chance of covering the run line, while the over/under total of 9.5 runs has a 50.7% chance of going over.
Reds vs. Cardinals odds [6/7/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Reds | Cardinals |
|---|---|---|
| Run Line | +1.5 (-155) | -1.5 (+130) |
| Moneyline | +128 | -152 |
| Total | o9.5 (+100) | u9.5 (-118) |
All odds are correct at the time of publication and are subject to change.
Reds vs. Cardinals picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Reds +1.5 | -155 |
| Moneyline | Reds | +128 |
| Total | Over 9.5 | +100 |
According to our MLB best bets, the top play to make on this game is Over 9.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Reds vs. Cardinals game-day updates and essential details
Sunday's MLB matchup between the Cardinals and Reds at Busch Stadium is scheduled to begin at 2:15 PM ET.
- Who: Cincinnati Reds vs. St. Louis Cardinals
- Date: Sunday, June 7, 2026
- Time: 2:15 PM ET/11:15AM PT
- Venue: Busch Stadium
Conclusion
We predict the Cardinals, with a 57.3% win probability, will likely beat the Reds in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



