Cubs vs. Brewers prediction: Why Milwaukee is favored to win Wednesday's MLB matchup [9/9/2026]
Dimers' simulation model projects a 53.8% win probability for the Brewers at American Family Field.

The Milwaukee Brewers will square off with the Chicago Cubs, in what is expected to be a close MLB game, at American Family Field on Wednesday, starting at 7:40 PM ET.
The Brewers will start Logan Henderson (9-3, 2.48 ERA), while the Cubs have opted for Kevin Gausman (9-11, 4.38 ERA).
Dimers' advanced MLB model gives the Brewers a slight edge with a 53.8% win probability over the Cubs.
This article offers a complete Cubs vs. Brewers prediction, including best bets and picks.
Cubs vs. Brewers prediction and odds
Our independent predictive model gives the Brewers a 53.8% chance of beating the Cubs.
According to our model, the Cubs (+1.5) have a 63.1% chance of covering the run line, while the over/under total of 7.5 runs has a 54.8% chance of going over.
Latest betting odds
We have researched the best MLB odds in America for this game, which are listed here:
- Run Line: Cubs +1.5 (-178) / Brewers -1.5 (+170)
- Moneyline: Cubs +117, Brewers -122
- Total: Over/Under 7.5 (-104/+101)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Brewers -1.5 @ 37¢ via Novig
- Moneyline: Cubs @ 46¢ via Novig
- Total: Over 7.5 @ 51¢ via Novig
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Wednesday's MLB action between the Brewers and Cubs at American Family Field is scheduled to begin at 7:40 PM ET.
- Who: Chicago Cubs vs. Milwaukee Brewers
- Date: Wednesday, September 9, 2026
- Time: 7:40 PM ET/4:40PM PT
- Venue: American Family Field
Conclusion
We predict the Brewers, with a 53.8% win probability, will likely beat the Cubs in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.




