Cubs vs. Marlins prediction: Why Cubs are favored to win Saturday's MLB matchup [9/5/2026]
Dimers' simulation model projects a 56.8% win probability for the Cubs at loanDepot park.

The Miami Marlins and Chicago Cubs will lock horns in MLB action at loanDepot park on Saturday, starting at 4:10 PM ET.
Ryan Gusto (1-3, 3.86 ERA) will start for the Marlins, up against Javier Assad (6-1, 3.46 ERA) for the Cubs.
Dimers' advanced MLB model projects the Cubs as the most likely winner in this Cubs vs. Marlins prediction.
This article offers further insights into Saturday's matchup, including best bets and picks.
Cubs vs. Marlins prediction and odds
Our famous predictive model gives the Cubs a 56.8% chance of beating the Marlins.
According to our model, the Marlins (+1.5) have a 55.1% chance of covering the run line, while the 8.5-run over/under has a 52.4% chance of going over.
Latest betting odds
We have sourced the best MLB odds in America for this game, which are listed here:
- Run Line: Cubs -1.5 (+135) / Marlins +1.5 (-132)
- Moneyline: Cubs -117, Marlins +125
- Total: Over/Under 8.5 (+106/-108)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Run line: Cubs -1.5 @ 43¢ via Novig
- Moneyline: Cubs @ 54¢ via Novig
- Total: Over 8.5 @ 49¢ via Novig
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & first pitch details
Saturday's MLB action between the Marlins and Cubs at loanDepot park is scheduled to commence at 4:10 PM ET.
- Who: Chicago Cubs vs. Miami Marlins
- Date: Saturday, September 5, 2026
- Time: 4:10 PM ET/1:10PM PT
- Venue: loanDepot park
Conclusion
We predict the Cubs, with a 56.8% win probability, will likely beat the Marlins in Saturday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



