Tigres UANL vs. Puebla prediction, odds, Liga MX picks [9/26/2026]

Liga MX action continues on Saturday at 11:10 PM ET as Puebla locks horns with Tigres UANL at Estadio Universitario.

Dimers' proven Liga MX model projects Tigres UANL as the most likely winner in this Tigres UANL vs. Puebla prediction.

This article offers an expanded analysis of Saturday's match, including best bets and picks.

Tigres UANL vs. Puebla prediction and odds

Using powerful machine learning and data, we have re-simulated the result of Saturday's Liga MX matchup between Tigres UANL and Puebla, forming part of our Liga MX predictions coverage.

Our famous predictive model indicates a 66.2% chance of Tigres UANL winning, a 14.3% chance for Puebla, and a 19.4% chance of a draw. Additionally, the over/under total of 2.5 goals has a 58.1% chance of going over., with a 51.6% chance that both teams score.

Latest betting odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

• Moneyline: Puebla +420, Tigres UANL -155
• Total Goals: Over/Under 2.5 (-106/-114)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Tigres UANL @ -155 via DraftKings
• Total Goals: Over 2.5 @ -106 via FanDuel

According to our best Liga MX bets, the top play to make on this game is Over 2.5 total goals.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score and BTTS projections

The top three most likely final scores, according to our model, are listed below, with a 2-0 Tigres UANL win being the most probable:

• Tigres UANL 2-0 Puebla (11.2% probability)
• Tigres UANL 1-0 Puebla (10.5%)
• Tigres UANL 2-1 Puebla (9.8%)

When it comes to the both teams to score (BTTS) market, we project a 51.6% chance of both sides finding the net and a 48.4% chance that at least one doesn’t.

Game info & kickoff details

Saturday's Liga MX game between Tigres UANL and Puebla at Estadio Universitario is scheduled to commence at 11:10 PM ET.

• Who: Tigres UANL vs. Puebla
• Date: Saturday, September 26, 2026
• Time: 11:10 PM ET/8:10PM PT
• Venue: Estadio Universitario

Conclusion

According to our computer model, Tigres UANL has a 66.2% win probability on Saturday, Puebla has a 14.3% win probability, and there is a 19.4% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary Liga MX prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.