Syracuse vs. Pittsburgh Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Syracuse vs. Pittsburgh NCAAF game on September 17, 2026. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Syracuse
Predicted score
21
:
31
Acrisure Stadium
Pittsburgh
Acrisure Stadium
Pre-Game Probabilities Last Update:

Spread

Syracuse +10.5
Spread
  • Syracuse
    52.2%
    FanDuelFanDuel
  • Pittsburgh
    47.8%
    BetRiversBetRivers

Syracuse vs. Pittsburgh: Detailed Breakdown

Matchup Overview

  • Teams: Syracuse vs. Pittsburgh
  • Date: Thursday, September 17, 2026
  • Time: 7:30 PM ET
  • Venue: Acrisure Stadium

Current betting odds

  • Spread: Pittsburgh favored at -10.5
  • Total (Over/Under): 51.5
  • Moneyline Odds: Syracuse +350, Pittsburgh -420

Dimers' win probabilities

  • Syracuse: 21%
  • Pittsburgh: 79%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Syracuse 21-31 Pittsburgh.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Syracuse a win probability of 21%, while Pittsburgh has a win probability of 79%.

Summary

According to our analysis, Pittsburgh is more likely to beat Syracuse in CFB action at Acrisure Stadium on Thursday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Syracuse vs. Pittsburgh predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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