Michigan State vs. Michigan: College Football Week 10 Prediction, Picks & Odds

Michigan State vs. Michigan: Detailed Breakdown

Matchup overview: College Football Week 10

• Teams: Michigan State vs. Michigan
• Date: Saturday, November 7, 2026
• Time: 7:30PM ET
• Venue: Michigan Stadium

Current betting odds

• Spread: Michigan State (+13.5, -109), Michigan (-13.5, -106)
• Moneyline: Michigan State +475, Michigan -506
• Total (Over/Under): 39.5 points (-106/-104)

Dimers’ win probabilities

• Michigan State: 14.4%
• Michigan: 85.6%

These probabilities come from two machine learning models that assess more than 100 data points for each college football matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this college football matchup is Michigan State 14-27 Michigan.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models

Our Prediction: Who Wins?

The numbers give the Michigan State a win probability of 14.4%, while the Michigan have a win probability of 85.6%.

Summary

Michigan State faces off against Michigan in college football action at Michigan Stadium on Saturday, November 7, 2026.

Our Michigan State vs. Michigan predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert college football predictions and the best college football bets today, while our in-depth analysis includes college football props, college football futures, college football odds, and the latest college football news.