Western Illinois vs. Southeast Missouri State prediction favors Southeast Missouri State to win in college football Week 7 [2026]

Using trusted machine learning and data, we have re-simulated the result of Western Illinois vs. Southeast Missouri State, forming part of our college football predictions coverage.

Our famous predictive model currently gives Southeast Missouri State a 68.0% chance of beating Western Illinois. Our predicted final score has Southeast Missouri State winning 29-22. According to our model, Southeast Missouri State (-6.5) has a 50.5% chance of covering the spread, while the 52.5-point over/under has an equal 50-50 chance of hitting.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Western Illinois +6.5 (-120) / Southeast Missouri State -6.5 (+113)
• Moneyline: Western Illinois +182, Southeast Missouri State -194
• Total: Over/Under 52.5 (+101/-122)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Southeast Missouri State -6.5 @ 47¢ via Novig
• Moneyline: Southeast Missouri State @ 66¢ via Novig
• Total: Over 52.5 @ +101 via DraftKings

According to our college football best bets, the top play to make on this game is Southeast Missouri State -6.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Southeast Missouri State and Western Illinois at Houck Field is scheduled to begin at 3:00 PM ET.

• Who: Western Illinois vs. Southeast Missouri State
• Date: Saturday, October 17, 2026
• Time: 3:00 PM ET/12:00PM PT
• Venue: Houck Field

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Conclusion

We predict Southeast Missouri State, with a 68.0% win probability, will likely beat Western Illinois in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.