Mercer vs. Samford prediction favors Mercer to win in college football Week 7 [2026]

Using innovative machine learning and statistical analysis, we have re-simulated the result of Mercer vs. Samford, forming part of our college football predictions coverage.

Our famous predictive model gives Mercer an 83.9% chance of defeating Samford. Our predicted final score has Mercer winning 32-18. According to our model, Samford (+14) has a 50.3% chance of covering the spread, while the over/under total of 50.5 points has a 50.2% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Mercer -14 (-113) / Samford +14 (-105)
• Moneyline: Mercer -590, Samford +425
• Total: Over/Under 50.5 (-110/-109)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Samford +14 @ -105 via DraftKings
• Moneyline: Mercer @ -590 via Caesars
• Total: Over 50.5 @ -110 via bet365

According to our best college football bets, the top play to make on this game is Samford +14 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Samford and Mercer at Pete Hanna Stadium is scheduled to begin at 7:00 PM ET.

• Who: Mercer vs. Samford
• Date: Saturday, October 17, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Pete Hanna Stadium

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Conclusion

We predict Mercer, with an 83.9% win probability, will likely beat Samford in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.