Southern California vs. Rutgers prediction: Why Southern California is favored to win in college football Week 3 [2026]

Using powerful machine learning and statistical analysis, we have re-simulated the outcome of Southern California vs. Rutgers, forming part of our college football predictions coverage.

Our leading predictive model currently gives Southern California a 96.4% chance of beating Rutgers. Our predicted final score has Southern California winning 39-17. According to our model, Southern California (-21.5) has a 52.5% chance of covering the spread, while the over/under total of 57.5 points has a 50.3% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Southern California -21.5 (-113) / Rutgers +21.5 (-105)
• Moneyline: Southern California -2100, Rutgers +1300
• Total: Over/Under 57.5 (-115/+100)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Southern California -21.5 @ -113 via BetRivers
• Moneyline: Southern California @ -2100 via DraftKings
• Total: Under 57.5 @ +100 via bet365

According to our college football best bets, the top play to make on this game is Southern California to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Rutgers and Southern California at SHI Stadium is scheduled to commence at 3:30 PM ET.

• Who: Southern California vs. Rutgers
• Date: Saturday, September 19, 2026
• Time: 3:30 PM ET/12:30PM PT
• Venue: SHI Stadium

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Conclusion

We predict Southern California, with a 96.4% win probability, will likely beat Rutgers in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.