Southeast Missouri State vs. Lindenwood prediction favors Southeast Missouri State to win in college football Week 6 [2026]

Using trusted machine learning and statistical analysis, we have re-simulated the result of Southeast Missouri State vs. Lindenwood, forming part of our college football predictions coverage.

Our leading predictive model gives Southeast Missouri State a 60.4% chance of beating Lindenwood. Our predicted final score has Southeast Missouri State winning 24-22. According to our model, the oddsmakers have got it right, and Southeast Missouri State and Lindenwood each have a 50% chance of covering the spread, while the over/under total of 45.5 points has a 53.5% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Southeast Missouri State -2.5 (-140) / Lindenwood +2.5 (+114)
• Moneyline: Southeast Missouri State -168, Lindenwood +135
• Total: Over/Under 45.5 (-110/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Lindenwood +2.5 @ +114 via DraftKings
• Moneyline: Southeast Missouri State @ -168 via DraftKings
• Total: Over 45.5 @ -110 via bet365

According to our college football best bets, the top play to make on this game is Lindenwood +2.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football matchup between Lindenwood and Southeast Missouri State at Hunter Stadium is scheduled to commence at 2:00 PM ET.

• Who: Southeast Missouri State vs. Lindenwood
• Date: Saturday, October 10, 2026
• Time: 2:00 PM ET/11:00AM PT
• Venue: Hunter Stadium

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Conclusion

We predict Southeast Missouri State, with a 60.4% win probability, will likely beat Lindenwood in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.