Old Dominion vs. App State prediction: Why Appalachian State is favored to win in college football Week 6 [2026]

Using powerful machine learning and data analysis, we have re-simulated the outcome of Old Dominion vs. App State, forming part of our college football predictions coverage.

Our famous predictive model currently gives Appalachian State a 78.6% chance of defeating Old Dominion. Our predicted final score has Appalachian State winning 28-18. According to our model, Appalachian State (-9.5) has a 53.1% chance of covering the spread, while the over/under total of 45.5 points has a 55.0% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Old Dominion +9.5 (-105) / App State -9.5 (-114)
• Moneyline: Old Dominion +300, App State -375
• Total: Over/Under 45.5 (-111/-107)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Appalachian State -9.5 @ -114 via bet365
• Moneyline: Appalachian State @ -375 via DraftKings
• Total: Over 45.5 @ -111 via bet365

According to our college football best bets, the top play to make on this game is Over 45.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between App State and Old Dominion at Kidd Brewer Stadium is scheduled to begin at 1:00 PM ET.

• Who: Old Dominion vs. Appalachian State
• Date: Saturday, October 10, 2026
• Time: 1:00 PM ET/10:00AM PT
• Venue: Kidd Brewer Stadium

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Conclusion

We predict Appalachian State, with a 78.6% win probability, will likely beat Old Dominion in Saturday's college football matchup.

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This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.