South Dakota vs. Murray State prediction: Why South Dakota is favored to win in college football Week 7 [2026]

Using powerful machine learning and statistical analysis, we have re-simulated the outcome of South Dakota vs. Murray State, forming part of our college football predictions coverage.

Our independent predictive model currently gives South Dakota a 98.1% chance of defeating Murray State. Our predicted final score has South Dakota winning 43-16. According to our model, Murray State (+28.5) has a 53.6% chance of covering the spread, while the over/under total of 60.5 points has a 52.2% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: South Dakota -28.5 (-113) / Murray State +28.5 (-107)
• Moneyline: South Dakota -2757, Murray State +2200
• Total: Over/Under 60.5 (-104/-115)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Murray State +28.5 @ -107 via Caesars
• Moneyline: South Dakota @ 96¢ via Novig
• Total: Under 60.5 @ -115 via Caesars

According to our college football best bets, the top play to make on this game is Murray State +28.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Murray State and South Dakota at Roy Stewart Stadium is scheduled to commence at 5:00 PM ET.

• Who: South Dakota vs. Murray State
• Date: Saturday, October 17, 2026
• Time: 5:00 PM ET/2:00PM PT
• Venue: Roy Stewart Stadium

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Conclusion

We predict South Dakota, with a 98.1% win probability, will likely beat Murray State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.