Delaware State vs. William & Mary prediction: Why William & Mary is favored to win in college football Week 1 [2026]
Dimers' simulation model projects a 70.1% win probability for William & Mary at Walter J. Zable Stadium at Cary Field.

William & Mary and Delaware State will lock horns in Week 1 college football action at Walter J. Zable Stadium at Cary Field on Saturday, commencing at 6:00 PM ET.
Dimers' proven college football model projects William & Mary as the most likely winner in this Delaware State vs. William & Mary prediction.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.
Delaware State vs. William & Mary prediction and odds
Our independent predictive model currently gives William & Mary a 70.1% chance of defeating Delaware State. Our predicted final score has William & Mary winning 31-22.
According to our model, Delaware State (+10.5) has a 54.4% chance of covering the spread, while the 57.5-point over/under has a 57.9% chance of staying under.
Latest betting odds
We have sourced the best college football odds in America for this game, which are listed here:
- Spread: Delaware State +10.5 (-125) / William & Mary -10.5 (-115)
- Moneyline: Delaware State +315, William & Mary -340
- Total: Over/Under 57.5 (-110/-110)
All odds are correct at the time of publication and are subject to change.
Model picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Spread: Delaware State +10.5 @ -125 via DraftKings
- Moneyline: Delaware State @ +315 via DraftKings
- Total: Under 57.5 @ -110 via bet365
According to our college football best bets, the top play to make on this game is Delaware State to win.
These picks are based on our probabilities matched against the implied probabilities from the current available odds.
Game info & kickoff details
Saturday's college football action between William & Mary and Delaware State at Walter J. Zable Stadium at Cary Field is scheduled to begin at 6:00 PM ET.
- Who: Delaware State vs. William & Mary
- Date: Saturday, September 5, 2026
- Time: 6:00 PM ET/3:00PM PT
- Venue: Walter J. Zable Stadium at Cary Field
College football Week 1 promos
Make the most of Dimers' Delaware State vs. William & Mary predictions by exploring the Underdog Fantasy offfer below
Conclusion
We predict William & Mary, with a 70.1% win probability, will likely beat Delaware State in Saturday's college football matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.




