Delaware State vs. William & Mary prediction: Why William & Mary is favored to win in college football Week 1 [2026]

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Written by Mac Douglass

Dimers' simulation model projects a 70.1% win probability for William & Mary at Walter J. Zable Stadium at Cary Field.

Delaware State takes on William & Mary in College Football action.
Delaware State vs. William & Mary college football gameday prediction for Saturday, September 5, 2026.

William & Mary and Delaware State will lock horns in Week 1 college football action at Walter J. Zable Stadium at Cary Field on Saturday, commencing at 6:00 PM ET.

Dimers' proven college football model projects William & Mary as the most likely winner in this Delaware State vs. William & Mary prediction.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, backed by the same system that has dominated college football and NFL betting markets across multiple seasons.

Delaware State vs. William & Mary prediction and odds

Using trusted machine learning and data, we have simulated the outcome of Delaware State vs. William & Mary, forming part of our college football predictions coverage.

Our independent predictive model currently gives William & Mary a 70.1% chance of defeating Delaware State. Our predicted final score has William & Mary winning 31-22.

According to our model, Delaware State (+10.5) has a 54.4% chance of covering the spread, while the 57.5-point over/under has a 57.9% chance of staying under.

 

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

  • Spread: Delaware State +10.5 (-125) / William & Mary -10.5 (-115)
  • Moneyline: Delaware State +315, William & Mary -340
  • Total: Over/Under 57.5 (-110/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

  • Spread: Delaware State +10.5 @ -125 via DraftKings
  • Moneyline: Delaware State @ +315 via DraftKings
  • Total: Under 57.5 @ -110 via bet365

According to our college football best bets, the top play to make on this game is Delaware State to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between William & Mary and Delaware State at Walter J. Zable Stadium at Cary Field is scheduled to begin at 6:00 PM ET.

  • Who: Delaware State vs. William & Mary
  • Date: Saturday, September 5, 2026
  • Time: 6:00 PM ET/3:00PM PT
  • Venue: Walter J. Zable Stadium at Cary Field

College football Week 1 promos

Make the most of Dimers' Delaware State vs. William & Mary predictions by exploring the Underdog Fantasy offfer below


Conclusion

We predict William & Mary, with a 70.1% win probability, will likely beat Delaware State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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