Duke vs. Michigan State Prediction, Picks & Odds

Dimers' Duke vs. Michigan State prediction for Tuesday, November 10, 2026. Win probabilities, projected final score, current odds, and picks from our college basketball machine learning model.
MEN'S CBB
CBB sport icon
MEN'S CBB
Duke DUKE
Predicted score
77
:
72
United Center
Michigan State MSU
United Center
Pre-Game Probabilities Last updated:

Spread

Michigan State +6.5
Spread
  • Duke
    42.3%
    CaesarsCaesars
  • Michigan State
    57.7%
    CaesarsCaesars

Duke vs. Michigan State prediction & analysis

Game overview: Men's college basketball Tuesday

  • Teams: Duke vs. Michigan State
  • Date: Tuesday, November 10, 2026
  • Tip-off: 7:00PM ET
  • Venue: United Center

Current betting odds

  • Spread: Duke (-6.5, -110), Michigan State (+6.5, -110)
  • Total (Over/Under): 148.5 points (-110/-110)
  • Moneyline: Duke -270, Michigan State +220

Dimers’ win probabilities

  • Duke: 69.2%
  • Michigan State: 30.8%

Our college basketball win probabilities come from a machine learning model that assesses each team's offensive and defensive performance, along with factors such as recent form, player availability, home-court advantage, and matchup dynamics.

The model uses these projections to forecast probabilities for the moneyline, spread, total points, and final score.

Projected Final Score

Our model projects the final score for this college basketball matchup as Duke 76 and Michigan State 71.

This is a margin of 5 points against a spread of 6.5, and a projected total of 147 points against a market line of 148.5.

A projected score is the middle of a range, not a forecast of the exact result. Use it to see how the game is likely to play out and how each side projects against the spread.

Our Prediction: Who Wins?

After extensive simulations, our model gives Duke a win probability of 69.2%, while Michigan State has a win probability of 30.8%.

Summary

According to our analysis, Duke is more likely to beat Michigan State in the men's college basketball game at United Center on Tuesday.

Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Duke vs. Michigan State predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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For further insights, explore our expert men's college basketball predictions and the best men's college basketball bets today, while our in-depth analysis includes men's college basketball props, men's college basketball futures, men's college basketball odds, and the latest men's college basketball news.