Syracuse vs. Indiana prediction, odds, pick for Nov. 9, 2026

Indiana is favored to beat Syracuse at Gainbridge Fieldhouse on Monday (6:30 PM ET), according to Dimers' men's college basketball model.

Our Syracuse vs. Indiana prediction gives the Orange a 64.1% chance of winning, but the latest odds suggest there's betting value on Syracuse to cover at +5.5.

Syracuse vs. Indiana key predictions

• Predicted score: Indiana 74-70 Syracuse
• Indiana win probability: 64.1%
• Syracuse win probability: 35.9%
• Syracuse +5.5 spread: 58.0% cover probability
• Under 146.5 points: 56.0% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

Syracuse vs. Indiana odds

Here are the best available odds across the moneyline, spread, and total points markets we track.

• Syracuse moneyline: +196 (Caesars Sportsbook)
• Indiana moneyline: -235 (BetMGM)
• Syracuse +5.5: -110 (Caesars Sportsbook)
• Indiana -5.5: -110 (Caesars Sportsbook)
• Over 146.5 points: -115 (FanDuel)
• Under 146.5 points: -105 (FanDuel)

Odds are subject to change and may vary by location.

Syracuse vs. Indiana pick: Syracuse +5.5 (-110)

Our model makes Indiana the likelier winner, but our best value bet is the Hoosiers to cover the +5.5 spread at -110 on Caesars Sportsbook.

Those odds give Syracuse an implied cover probability of 52.4%, while our model puts it at 58.0%.

That's a 5.7% edge (accounting for rounding), the largest across the moneyline, spread, and total points markets for this game.

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Syracuse vs. Indiana game details

• Matchup: Syracuse Orange vs. Indiana Hoosiers
• Date: Monday, November 9, 2026
• Time: 6:30 PM ET
• Venue: Gainbridge Fieldhouse
• Tournament details: 2026 NBA Cup

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.