DePaul vs. Northwestern prediction, odds, pick for Nov. 13, 2026

DePaul is favored to beat Northwestern at Welsh-Ryan Arena on Friday (9:00 PM ET), according to Dimers' men's college basketball model.

Our DePaul vs. Northwestern prediction gives the Blue Demons a 52.2% chance of winning, and the latest odds suggest there's betting value on the DePaul moneyline, too.

DePaul vs. Northwestern key predictions

• Predicted score: DePaul 69-68 Northwestern
• DePaul win probability: 52.2%
• Northwestern win probability: 47.8%
• DePaul +1.5 spread: 54.8% cover probability
• Over 137 points: 52.9% probability

Our men's college basketball predictions project each team's final score using offensive and defensive efficiency, recent performance, long-term trends, and matchup-specific factors.

We calculate win, spread, and total probabilities based on these projections and historical CBB scoring patterns, then compare them with the latest odds to find betting value.

DePaul vs. Northwestern odds

Below are the best available odds across the moneyline, spread, and total points markets.

• DePaul moneyline: -102 (FanDuel)
• Northwestern moneyline: -105 (BetMGM)
• DePaul +1.5: -115 (FanDuel)
• Northwestern -1.5: +110 (DraftKings)
• Over 137 points: -110 (Caesars Sportsbook)
• Under 137 points: -110 (Caesars Sportsbook)

Odds are subject to change and may vary by location.

DePaul vs. Northwestern pick: DePaul ML (-102)

Our model makes DePaul the likelier winner, and our best value bet is the Blue Demons moneyline at -102 on FanDuel, too.

Those odds give DePaul an implied win probability of 50.5%, while our model rates it at 52.2%.

That's a 1.7% edge, the largest across the moneyline, spread, and total points markets.

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• Best bets across the moneyline, spread, and total points markets
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DePaul vs. Northwestern game details

• Matchup: DePaul Blue Demons vs. Northwestern Wildcats
• Date: Friday, November 13, 2026
• Time: 9:00 PM ET
• Venue: Welsh-Ryan Arena

About this prediction

This preview uses predictions from our men's college basketball models, presented through a template written by our editorial team. Matchup details fill in automatically.

Predictions are estimates, not guarantees, and can change as new information comes in, such as injury news or lineup changes. Learn how our predictions work.

Dimers encourages responsible gambling.