Bets 
Reds vs. Cardinals prediction: St. Louis favored to win Saturday's MLB matchup [6/6/2026]
MLB
Cardinals vs. Marlins Prediction, Picks and Odds
Our detailed prediction and analysis for the Cardinals vs. Marlins MLB game on April 21, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
Start your FREE 3-Day trial of Dimers Pro 
FINAL
MLB
FINAL
MLB
5
3
Apr 21, 10:40PM loanDepot park
Apr 21, 10:40PM loanDepot park
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Bets
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cardinals | 1 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 5 | 10 | 1 |
Marlins | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 8 | 0 |
Live Probabilities
Moneyline
Over / Under
Run Line
Win %
100%
0%
Win Probability
Last At Bat
Outs
Xavier Edwards lines out to left field to Nathan Church.
Quick Box Score
Hitting
Pitching
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | J. Wetherholt | 2B | 4 | 2 | 1 | 0 | 0 | 1 | 2 | .250 | 0.900 |
| 2 | I. Herrera | DH | 5 | 0 | 2 | 0 | 0 | 0 | 2 | .400 | 0.800 |
| 3 | A. Burleson | 1B | 4 | 1 | 2 | 2 | 0 | 0 | 1 | .500 | 1.250 |
| 4 | J. Walker | RF | 4 | 0 | 0 | 0 | 0 | 0 | 2 | .000 | 0.000 |
| 5 | N. Gorman | 3B | 4 | 0 | 1 | 1 | 0 | 0 | 2 | .250 | 0.500 |
| 6 | M. Winn | SS | 4 | 1 | 2 | 0 | 0 | 0 | 0 | .500 | 1.250 |
| 7 | N. Church | LF | 4 | 1 | 2 | 2 | 1 | 0 | 0 | .500 | 1.750 |
| 8 | P. Pagés | C | 4 | 0 | 0 | 0 | 0 | 0 | 2 | .000 | 0.000 |
| 9 | V. Scott | CF | 3 | 0 | 0 | 0 | 0 | 1 | 1 | .000 | 0.250 |
| No. | Player | Pos | AB | R | H | RBI | HR | BB | SO | AVG | OPS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | J. Marsee | CF | 4 | 1 | 3 | 1 | 1 | 0 | 0 | .750 | 2.300 |
| 2 | K. Stowers | RF | 4 | 0 | 0 | 0 | 0 | 1 | 1 | .000 | 0.200 |
| 3 | O. Lopez | SS | 5 | 0 | 0 | 0 | 0 | 0 | 1 | .000 | 0.000 |
| 4 | X. Edwards | 2B | 4 | 1 | 2 | 0 | 0 | 1 | 0 | .500 | 1.100 |
| 5 | L. Hicks | C | 3 | 1 | 0 | 0 | 0 | 1 | 0 | .000 | 0.250 |
| 6 | A. Ramírez | DH | 4 | 0 | 0 | 0 | 0 | 0 | 2 | .000 | 0.000 |
| 7 | J. Sanoja | 3B | 0 | 0 | 0 | 0 | 0 | 1 | 0 | .000 | 1.000 |
| 8 | H. Hernández | LF | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 1.000 | 2.000 |
| 9 | C. Norby | 1B | 4 | 0 | 1 | 0 | 0 | 0 | 2 | .250 | 0.500 |
Featured offers
Swipe across to view more offers
FEATURED
New DraftKings Customers: Bet $5, Get $200 in Bonus Bets Instantly
T&Cs apply.
How to claim
RECOMMENDED
Double Your Winnings on your Next 10 Wagers. Up to $25 Max Bet Per Boost
T&Cs apply.
How to claim
NEW PLAYERS
Bet $5, Get $150 in Bonus Bets if your bet wins!
T&Cs apply.
How to claim
RECOMMENDED
Deposit $20, Get $50 in Trading Bonus!
T&Cs apply.
How to claim
LIMITED-TIME
Register with code DIMERS150 to unlock $150 in bonus bets by winning your first $10 bet
T&Cs apply.
How to claim
NEW PLAYERS
Get $350 in Bonus Bets Guaranteed - When You Bet $5 for 7 Days!
T&Cs apply.
How to claim
RECOMMENDED
Use Code DIMERS to Get up to $100 in Bonuses by Trading in Your First 7 Days!
T&Cs apply.
How to claim
TRENDING
Bet $10 Get $365 Win or Lose
T&Cs apply.
How to claim
NEW PLAYERS
Get Up To $250 Back in Bonus Bets If Your First Bet Loses
T&Cs apply.
How to claim
Cardinals vs. Marlins: Detailed Breakdown
Matchup Overview
- Teams: Cardinals vs. Marlins
- Date: Tuesday, April 21, 2026
- Time: 6:40 PM ET
- Venue: loanDepot park
Current Betting Odds
- Spread: Marlins favored at -1.5
- Total (Over/Under): 8.5
- Moneyline Odds: Cardinals +111, Marlins -111
Dimers' Win Probabilities
- Cardinals: 47%
- Marlins: 53%
Dimers' predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.
Our Prediction: Who Wins?
After extensive simulations, our model gives the Cardinals a win probability of 47%, while the Marlins have a win probability of 53%. Discover the best spread, over/under, and moneyline odds for the game on this page.
Summary
According to our analysis, the Marlins are more likely to beat the Cardinals in the MLB game at loanDepot park on Tuesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.
Our Cardinals vs. Marlins predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.
For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.
For further insights, explore our expert MLB predictions and the best MLB bets today, while our in-depth analysis includes MLB props, MLB futures, MLB odds, and the latest MLB news.
