White Sox vs. Cardinals: MLB Prediction & Analysis

Our detailed prediction and analysis for the White Sox vs. Cardinals MLB game on Saturday, September 12, 2026 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.
FINAL
MLB
FINAL
MLB sport icon
MLB
White Sox
Sean Newcomb 2-4, 2.71 ERA
6
5
Busch Stadium
Cardinals
Kyle Leahy 10-4, 3.41 ERA
Busch Stadium
1 2 3 4 5 6 7 8 9 RHE
White Sox
0 0 0 1 3 0 0 0 2 6 6 2
Cardinals
0 3 0 1 0 0 0 1 0 5 8 1
Live Probabilities
Win %
  • White Sox
    100%
  • Cardinals
    0%
Win Probability
Baseball infield diamond diagram
Last At Bat
Outs
Leo Bernal grounds out to shallow infield, Luisangel Acuña to Munetaka Murakami.
Quick Box Score
White Sox Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Rogers C0000000.0000.000
2 B. Doyle CF0100000.0000.000
3 M. Vargas 3B5110003.2000.400
4 M. Murakami 1B4111012.2500.650
5 R. Grichuk DH4112102.2501.250
6 T. Peters LF4011001.2500.650
7 C. Meidroth 2B3000011.0000.250
8 L. Acuña SS0000000.0000.000
9 B. Montgomery RF3000011.0000.250
Cardinals Hitting
No.PlayerPosABRHRBIHRBBSOAVGOPS
1 J. Fermín LF2001022.0000.400
2 I. Herrera DH3000021.0000.400
3 A. Burleson 1B4000012.0000.200
4 J. Walker PH1000001.0000.000
5 L. Bernal C5111101.2001.000
6 R. Urías 3B0000000.0000.000
7 T. Saggese 2B4110001.2500.500
8 M. Winn SS4122002.5001.250
9 N. Church CF4031000.7501.750

White Sox vs. Cardinals: Detailed Breakdown

Matchup overview: MLB Saturday

  • Teams: CHI White Sox White Sox vs. St. Louis Cardinals
  • Date: Saturday, September 12, 2026
  • Time: 7:15PM ET
  • Venue: Busch Stadium

Current betting odds

  • Spread: White Sox (-1.5, +155), Cardinals (+1.5, -163)
  • Moneyline: White Sox +100, Cardinals +104
  • Total (Over/Under): 8.5 runs (+104/-108)

Dimers’ win probabilities

  • White Sox: 48.4%
  • Cardinals: 51.6%

Dimers' predictive MLB model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Our Prediction: Who Wins?

After extensive simulations, our model gives the White Sox a win probability of 48.4%, while the Cardinals have a win probability of 51.6%.

Summary

According to our analysis, the Cardinals are more likely to beat the White Sox in the MLB game at Busch Stadium on Saturday. Discover the best run line, over/under and moneyline odds, picks and probabilities for the game on this page.

Our White Sox vs. Cardinals predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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