Kansas vs. Iowa State Prediction, Picks and Odds

Our in-depth analysis offers a comprehensive prediction for the Kansas vs. Iowa State NCAAF game on November 22, 2025. Drawing from 10,000 simulations, we provide expert picks, betting odds, and insights.

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Kansas
14
38
Nov 22, 5PM Jack Trice Stadium
Iowa State
Nov 22, 5PM Jack Trice Stadium
In-Play ProbabilitiesIn-Play
Game PredictionsPre-Game
Dimers Pro Best Bets
Live Probabilities
Spread
Over / Under
Moneyline
KansasKU
Win %
0%
100%
Iowa StateISU
Win Probability
TEAM1234T
Kansas
0 0 14 0 14
Iowa State
7 10 14 7 38
1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0 1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0
Iowa State
Kansas
End of Game
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Kansas vs. Iowa State: Detailed Breakdown

Matchup Overview

  • Teams: Kansas vs. Iowa State
  • Date: Saturday, November 22, 2025
  • Time: 12:00 PM ET
  • Venue: Jack Trice Stadium

Current betting odds

  • Spread: Iowa State favored at -3.5
  • Total (Over/Under): 55.5
  • Moneyline Odds: Kansas +140, Iowa State -158

Dimers' win probabilities

  • Kansas: 38%
  • Iowa State: 62%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this college football matchup is Kansas 24-28 Iowa State.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Kansas a win probability of 38%, while Iowa State has a win probability of 62%.

Summary

According to our analysis, Iowa State is more likely to beat Kansas in CFB action at Jack Trice Stadium on Saturday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Kansas vs. Iowa State predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee.

Explore our expert college football predictions and the best college football bets today for more insights and betting opportunities.

Our in-depth analysis includes college football player props and college football futures, as well as constantly updated college football odds and the latest college football news.