Karen Khachanov vs. Alexander Blockx prediction, odds, picks for US Open 2026

Using powerful machine learning and statistical analysis, we have re-simulated the outcome of Wednesday's Khachanov-Blockx men's singles match, forming part of our tennis predictions coverage.

Our independent predictive model gives Khachanov a 63% chance of defeating Blockx in the US Open 2026.

Additionally, Khachanov has a 60% chance of winning the first set, according to our model.

Latest betting odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

• Moneyline: Alexander Blockx +137, Karen Khachanov -175
• First Set: Khachanov -152, Blockx +120

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Khachanov @ -175 via DraftKings
• First Set: Khachanov @ -152 via DraftKings

According to our tennis best bets, the top play to make on this match is Karen Khachanov to win the first set.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & first serve details

The US Open 2026 match between Karen Khachanov and Alexander Blockx is scheduled to commence on Wednesday at 11:30 AM ET.

• Who: Karen Khachanov vs. Alexander Blockx
• Date: Wednesday, September 9, 2026
• Approx. Time: 11:30 AM ET/8:30AM PT
• Tournament: US Open Men's Singles 2026
• Round: Quarterfinals

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Conclusion

We predict Karen Khachanov, with a 63% win probability, will likely beat Alexander Blockx at the US Open 2026.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.