Newcastle Knights vs. Sydney Roosters prediction: Roosters favored to win Friday's NRL Round 21 matchup [7/24/2026]
Get Newcastle Knights vs Sydney Roosters predictions for NRL Friday.
The Newcastle Knights and Sydney Roosters will lock horns in the National Rugby League (NRL) at McDonald Jones Stadium on Friday, starting at 4:00 AM ET.
Based on updated simulation results, Dimers' advanced NRL model projects the Roosters as the most likely winner of the Roosters vs. Knights game.
This article offers an expanded analysis of Friday's matchup, including best bets and picks.
Knights vs. Roosters prediction: Who will win Round 21 game?
Our independent predictive model currently gives the Roosters a 68.6% chance of beating the Knights.
According to our model, the Roosters (-4.5) have a 55.5% chance of covering the spread, while the 45.5-point over/under has a 50.2% chance of staying under,.
Roosters vs. Knights odds
We have researched the best NRL odds in America for this game, which are listed here:
| Bet Type | Roosters | Knights |
|---|---|---|
| H2H (Moneyline) | -161 | +125 |
| Line (Spread) | -4.5 (-105) | +4.5 (-120) |
| Total | o45.5 (-114) | u45.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Roosters vs. Knights picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Roosters -4.5 | -105 |
| Moneyline | Roosters | -161 |
| Total | Under 45.5 | -114 |
According to our NRL best bets, the top play to make on this game is Roosters to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Knights vs. Roosters game-day updates and essential details
Friday's Australian rugby league game between the Knights and Roosters at McDonald Jones Stadium is scheduled to start at 4:00 AM ET.
- Who: Sydney Roosters vs. Newcastle Knights
- Date: Friday, July 24, 2026
- Time: 4:00 AM ET/1:00AM PT
- Venue: McDonald Jones Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Conclusion
We predict the Roosters, with a 68.6% win probability, will likely beat the Knights in Friday's NRL matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Damien Souness is Chief Experience Officer at Cipher Sports Technology Group, helping lead sports media brands such as Dimers. He specializes in creating trustworthy and data-driven content for sports fans, with experience working for globally recognized sports and media organizations.
