Women's college basketball picks today: Wednesday's best bets include Eastern Kentucky vs. Louisville play [12/17/2025]

Eastern Kentucky +41.5 (-112)

• Edge: 20.4%
• Probability: 73.2%
• Matchup: Eastern Kentucky vs. Louisville (6:00PM ET, Wednesday)

Our model has identified value on Eastern Kentucky +41.5 at -112 odds. A 73.2% probability produces an edge of 20.4%, making this the strongest play for today's women's college basketball slate.

North Carolina-Wilmington +54.5 (-110)

• Edge: 15.6%
• Probability: 68%
• Matchup: North Carolina-Wilmington vs. North Carolina (8:00PM ET, Wednesday)

North Carolina-Wilmington +54.5 carries a 15.6% edge and a probability of 68% at -110 odds, according to our model.

Mississippi Valley State +65.5 (-110)

• Edge: 13.6%
• Probability: 66%
• Matchup: Mississippi Valley State vs. Ole Miss (5:00PM ET, Wednesday)

Mississippi Valley State +65.5 vs. Ole Miss at -110 odds shows a 13.6% edge, supported by a 66% probability in simulations.

Northwestern State vs. Texas under 140.5 points (-110)

• Edge: 11.0%
• Probability: 63.4%
• Matchup: Northwestern State vs. Texas (9:00PM ET, Wednesday)

An 11.0% edge and 63.4% probability make Northwestern State vs. Texas under 140.5 points at a value play in the Northwestern State vs. Texas matchup, per our model.

North Carolina-Wilmington vs. North Carolina under 139.5 points (-110)

• Edge: 8.3%
• Probability: 60.6%
• Matchup: North Carolina-Wilmington vs. North Carolina (8:00PM ET, Wednesday)

North Carolina-Wilmington vs. North Carolina under 139.5 points at -110 odds presents a 8.3% edge, with simulations resulting in a probability of 60.6%.

Northwestern State +50.5 (-110)

• Edge: 6.6%
• Probability: 59%
• Matchup: Northwestern State vs. Texas (9:00PM ET, Wednesday)

Our model finds value on Northwestern State +50.5 at -110 odds, supported by an edge of 6.6%.

NCAAW best bets summary: Wednesday, 12/17/2025

As of 12:04PM ET, here are our top women's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Eastern Kentucky vs. Louisville	Eastern Kentucky +41.5	-112 @ FanDuel	20.4%	73.2%
North Carolina-Wilmington vs. North Carolina	North Carolina-Wilmington +54.5	-110 @ FanDuel	15.6%	68%
Mississippi Valley State vs. Ole Miss	Mississippi Valley State +65.5	-110 @ DraftKings	13.6%	66%
Northwestern State vs. Texas	Under 140.5 Points	-110 @ DraftKings	11.0%	63.4%
North Carolina-Wilmington vs. North Carolina	Under 139.5 Points	-110 @ FanDuel	8.3%	60.6%
Northwestern State vs. Texas	Northwestern State +50.5	-110 @ DraftKings	6.6%	59%

List of upcoming women's college basketball games to bet on now

• Jacksonville vs. Texas Tech (12:30PM ET, Wednesday)
• Florida A&M vs. Florida (3:00PM ET, Wednesday)
• Mississippi Valley State vs. Ole Miss (5:00PM ET, Wednesday)
• Tulane vs. Alabama (5:00PM ET, Wednesday)
• Jacksonville State vs. Saint Louis (5:00PM ET, Wednesday)
• Eastern Kentucky vs. Louisville (6:00PM ET, Wednesday)
• Marquette vs. Connecticut (7:00PM ET, Wednesday)
• Kansas City vs. Arkansas (7:30PM ET, Wednesday)
• Evansville vs. Belmont (7:30PM ET, Wednesday)
• North Carolina-Wilmington vs. North Carolina (8:00PM ET, Wednesday)

Conclusion

Our women's college basketball best bets are locked and loaded for December 17, 2025, featuring plays such as Eastern Kentucky +41.5 and North Carolina-Wilmington +54.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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