South Dakota State vs. Duke prediction: Duke favored to win women's college basketball matchup [12/18/2025]

Duke and South Dakota State will meet in the women's college basketball at Cameron Indoor Stadium on Thursday, with tipoff at 7:00 PM ET.

Based on updated simulations, Dimers' new women's basketball model projects Duke as the most likely winner of the South Dakota State vs. Duke game.

This article offers a closer look at Thursday's matchup, including best bets and picks.

South Dakota State vs. Duke prediction: Who will win?

Using innovative machine learning and data, we have simulated the result of Thursday's women's basketball game between South Dakota State and Duke 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model currently gives Duke a 94% chance of beating South Dakota State.

According to our model, the over/under total of 137.5 points has a 64% chance of staying under.

South Dakota State vs. Duke odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Dakota State vs. Duke picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: