Penn State vs. South Carolina prediction: South Carolina favored to win women's college basketball matchup [12/14/2025]

South Carolina will take on Penn State in women's college basketball action at Colonial Life Arena on Sunday, starting at 3:30PM ET.

Based on the latest simulation results, Dimers' new women's basketball model projects South Carolina as the most likely winner of the Penn State vs. South Carolina game.

This article offers further insights into Sunday's matchup, including best bets and picks.

Penn State vs. South Carolina prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Sunday's women's basketball game between Penn State and South Carolina 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model currently gives South Carolina a 99% chance of defeating Penn State.

According to our model, the over/under total of 159.5 points has a 61% chance of staying under.

Penn State vs. South Carolina odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Penn State vs. South Carolina picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: