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Penn State vs. South Carolina prediction: South Carolina favored to win women's college basketball matchup [12/14/2025]

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Written by Ryan Leaver

Get Penn State vs South Carolina predictions for college basketball Sunday.

Penn State-South Carolina Predictions and Game Preview.
Penn State vs. South Carolina women's college basketball prediction for Sunday, December 14, 2025.

South Carolina will take on Penn State in women's college basketball action at Colonial Life Arena on Sunday, starting at 3:30PM ET.

Based on the latest simulation results, Dimers' new women's basketball model projects South Carolina as the most likely winner of the Penn State vs. South Carolina game.

This article offers further insights into Sunday's matchup, including best bets and picks.

Penn State vs. South Carolina prediction: Who will win?

Using trusted machine learning and data, we have simulated the outcome of Sunday's women's basketball game between Penn State and South Carolina 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model currently gives South Carolina a 99% chance of defeating Penn State.

According to our model, the over/under total of 159.5 points has a 61% chance of staying under.

 

Penn State vs. South Carolina odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Penn State South Carolina
Spread +42.5 (-110) -42.5 (-110)
Total o159.5 (-110) u159.5 (-110)

All odds are correct at the time of publication and are subject to change.

Penn State vs. South Carolina picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Penn State +42.5 -110
Total Under 159.5 -110

According to our women's college basketball best bets, the top play to make on this game is under 159.5 points.

 

Penn State vs. South Carolina game-day updates and essential details

Sunday's women's basketball matchup between South Carolina and Penn State at Colonial Life Arena is scheduled to start at 3:30PM ET.

  • Who: Penn State vs. South Carolina
  • Date: Sunday, December 14, 2025
  • Time: 3:30PM ET/12:30PM PT
  • Venue: Colonial Life Arena

Conclusion

We predict South Carolina, with a 99% win probability, will likely beat Penn State on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Penn State vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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